Abstract:Objective To investigate and analyze the prevalence of HCV infection and its risk factors among drug users in Changde City. Methods The objects were recruited by cluster samlping method in 2010-2014. Demographic and behavioral information was obtained by an anonymous questionnaire survey. Multi-factor logistic regression model was used to analyze the risk factors of HCV infection. Results The HCV infection rate of the 2,000 drug users surveyed was 54.9%, with the HCV infection rate of 78.7% in the injected drug users. Multi-factor logistic regression analysis showed that intravenous drug abuse and sharing needles were closely associated with the HCV infection rate; moreover, the longer the time of injecting drug abuse and sharing needles, the higher the HCV infecton rate. Conclusions The infecton rate of HCV in drug users in Changde City shows an increasing tendency from 2010-2014. Intravenous drug abuse and sharing needles are the risk factors for HCV infection.
[1] Lavanchy D.Global burden of hepatitis C[J].Liver Int,2009,29(Supp11):74-81. [2] Ward JW. The epidemiology of chronic hepatitis C and one-time hepatitis C virus testing of persons born during 1945 to 1965 in the United States[J]. Clin Liver Dis,2013,17(1):1-11. [3] 赵莹莹,邢卉春,成军. 2012 年亚太肝脏协会 HCV 感染管理策略专家共识解读[J]. 中国肝脏病杂志,2012,4(1):33-37. [4] 刘涛,陶毓新,钱迟华,等. 苏州市强制戒毒人群 HIV 梅毒 HCV感染情况与相关行为调查[J]. 中国艾滋病性病,2012,18(2):92-103. [5] 张华源,周伴群,焦亮.珠海市斗门区吸毒人群丙肝感染现状和影响因素研究[J].实用预防医学,2013,20(8):956-959. [6] 苏迎盈,汪宁. 丙型肝炎病毒感染主要危险因素 Meta 分析[J].中华流行病学杂志,2011,32(9):940-944. [7] 夏玛丽,刘佳,孟炜,等.静脉注射吸毒人群丙肝病毒感染的非条件logistic回归分析[J].中国卫生检验杂志,2014,24(12):1792-1793.