1. Jinan Municipal Center for Disease Control and Prevention, Jinan, Shandong 250021, China; 2. The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital), Jinan, Shandong 250014, China
Abstract：Objective To explore the risk factors for onset of severe fever with thrombocytopenia syndrome (SFTS) in Jinan City, and to provide a reference basis for prevention and control of the disease. Methods Case-control study method was used to enroll confirmed patients with SFTS in Jinan City during 2014-2022 into the case group, and healthy residents living near the patients' residence in the same period were selected proportionally as the control group. Their related data were collected. Univariate and multivariable logistic regression analyses were performed to identify risk factors. Results A total of 632 SFTS cases and 1,571 healthy residents were enrolled into this study. Multivariable logistic regression analysis revealed that tick bite history (OR=153.123, 95%CI:14.069-1,666.532), engaging in field work (OR=3.948, 95%CI:1.019-15.298), having weeds/shrubs around working areas (OR=3.603, 95%CI:1.204-10.785) and having ticks in the field (OR=3.120, 95%CI:1.071-9.089) were risk factors forSFTS onset (P<0.05). Taking protective measures in field operations (OR=0.193, 95%CI:0.080-0.465) and having family members or neighbors with SFTS (OR=0.003, 95%CI:0.000-0.025) were protective factors for SFTS onset (P<0.05). Conclusion Tick bite history, engaging in field work, having weeds and shrubs around working areas and having ticks in the field are main risk factors for SFTS onset. Health education and behavioral interventions should be strengthened in the high-risk population so as to prevent and control SFTS onset.
2024, Vol. 31 
