Abstract:Objective To analyze the risk factors affecting periodontal disease onset and construction of a nomogram prediction model. Methods One hundred periodontal tissue disease patients who attended Beijing Hospital of Traditional Chinese Medicine from April 2018 to November 2021 were selected as the research subjects, namely, the observation group, and another 100 patients undergoing health check-ups at the hospital during the same period were selected as the control group. The baseline data of the two groups were recorded. Multi-factor logistic regression analysis was used to identify the risk factors influencingonsetof periodontal tissue disease, and a nomogram prediction model was constructed. Internal data were employed to verify the clinical efficacy of the nomogram model. Results In the comparison of general information such as age and gender between the two groups, the differences were not statistically significant (P>0.05). Compared with the control group, the observation group had shorter brushing time, more smokers and irregular brushes, fewer early and late brushes and fewer rinses after meals, all with statistically significant differences (P<0.05). The area under the curve (AUC) for brushing time was 0.787, and the best cut-off value 2 minutes. The time spent brushing (≤2 min), smoking (yes), irregular brushing (yes), brushing early and late (no) and rinsing after meals (no) were risk factors for the development of periodontal disease (P<0.05). The internal validation results showed that the C-index of the nomogram model for predicting the risk of developing periodontal disease in the patients was 0.733 (95%CI:0.669-0.801). DCA results displayed that the model predicted a risk threshold of >0.07 for patient morbidity. Conclusion Brushing time (≤2 min), smoking (yes), irregular brushing (yes), brushing early and late (no) and rinsing after meals (no) are risk factors for the development of periodontal disease in the patients, moreover, the prediction model constructed based on the risk variables in this study can better predict the patients' development of the disease.
陈洁点, 丁丹丹. 牙周病发病危险因素分析及列线图预测模型的构建[J]. 实用预防医学, 2024, 31(2): 185-188.
CHEN Jiedian, DING Dandan. Risk factors for onset of periodontal disease and construction of a predictive model for columnar maps. , 2024, 31(2): 185-188.
[1] 郑明珠,张曼华,侯晓菲,等.老年Ⅱ型糖尿病患者口腔健康状况及相关生活质量影响因素分析[J].实用预防医学,2022,29(4):487-490. [2] 孟焕新. 牙周病学[M].第4版.北京:人民卫生出版社, 2014:1-107. [3] 杨捷,王耀志,沈晓丽,等.超声刮治同步替硝唑冲洗治疗慢性牙周炎的效果及对龈沟液因子水平的影响[J].河北医科大学学报,2018,39(2):189-192. [4] 李广有.青少年牙周炎的防治[J].中外健康文摘,2010,7(22):121-122. [5] 黄玉钊. 浅谈青少年牙周炎[J].中外健康文摘,2008,5(21):8-9. [6] Schenkein HA, Koertge TE, Brooks CN, et al. IL-17 in sera from patients with aggressive periodontitis [J].J Dent Res,2010,89(9):1120-1125. [7] 许丽华,许尧生,杨冬茹,等.辅助性 T 细胞亚群与牙周炎的免疫损伤机制[J].国际口腔医学杂志,2017,44(1):98-102. [8] Bahit MC, Lopesr D, Wojdyla DM, et al. Non-major bleeding with apixaban versus warfar in inpatients with atrial fibrillation[J]. Heart,2017,103(8):623-628. [9] 黄维佳,曹健斌,李逢昌,等.接受EGFR-TKIs治疗的EGFR突变阳性非小细胞肺癌患者预后预测列线图模型构建及验证[J].实用心脑肺血管病杂志,2022,30(10):33-39. [10] Acharya AB,Satyanarayan A,Thakur SL,et al.Status of association studies linking diabetes mellitus and periodontal disease in India[J].Int J Diabetes Dev Ctries,2010,30(2):69-74. [11] 李佳锐,孔令匀博,李梦琦,等.750名湘西自治州土家族居民口腔健康状况及口腔健康认知调查[J].实用预防医学,2023,30(2):205-207. [12] Lamster IB,DePaola DP,Oppermann RV,et al.The relationship of periodontal disease to diseases and disorders at distant sites: communication to health care professionals and patients[J].J Am Dent Assoc,2008,139(10):1389-1397. [13] Peruzzo DC,Benatti BB,Ambrosano GM,et al.A systematic review of stress and psychological factors as possible risk factors for periodontal disease[J]. J Periodontol,2007,78(8):1491-1504. [14] 吕达,孟焕新,徐莉,等.侵袭性牙周炎患者治疗后失牙的预测模型[J].北京大学学报(医学版),2013,45(3):480-483. [15] 嵇兆丽.系统口腔护理干预对牙周病患者口腔保健知识认知率的影响[J].航空航天医学杂志,2021,32(10):1236-1237. [16] 马思佳,彭艺,吴剑花,等. 云南省耿马县佤族成人牙周健康状况调查及危险因素[J].昆明医科大学学报,2022,43(4):26-31. [17] Foia L,Toma V,Ungureanu D,et al. Relationship diabetes mellitus periodontal disease:etiology and risk factors[J].Rev Med Chir Soc Med Nat Iasi,2007,111(3):748-753. [18] Chávarry NG,Vettore MV,Sansone C,et al.The relationship between diabetes mellitus and destructive periodontal disease:a meta analysis[J].Oral Health Prev Dent,2009,7(2):107-127. [19] Okamoto Y,Tsuboi S,Suzuki S,et al.Effects of smoking and drinking habits on the incidence of periodontal disease and tooth loss among Japanese males:a 4-yr longitudinal study[J].J Periodontal Res,2006,41(6):560-566. [20] 陈璇,吴昕彧,梁悦娥,等.复方金银花中药漱口水对大鼠实验性牙周炎的作用研究[J].兰州大学学报(医学版),2022,48(10):36-42. [21] 王卫东,董苁蓉,李蒙.体检人群中牙周炎危险因素的分析[J].中国热带医学,2014,14(5):571-573. [22] 周晓颖,赵翚,倪凌晨,等.牙周炎的发病相关因素及预防措施分析[J].中国现代医生,2015,53(22):67-69,73. [23] 谢红军,闫长安.236例牙周病相关危险因素logistic回归分析[J].吉林医学,2011,32(15):2965-2967.