1. Beijing Obstetrics and Gynecology Hospital, Capital Medical University/Beijing Maternal and Child Health Care Hospital, Beijing 100026, China; 2. Beijing Municipal Health Big Data and Policy Research Center, Beijing 100034, China
Abstract:Objective To investigate the relationship between socio-cultural characteristics of pregnant women with gestational diabetes mellitus (GDM) and the risk of macrosomia, and to provide a basis for the primary prevention of macrosomia. Methods This study was a retrospective cohort study. According to the unique identification code in the system, the maternal information with delivery dates between April 1, 2019 and January 31, 2020 collected from Beijing Maternal and Child Health Information System was matched with the first page data of inpatient medical records from the First Page Information System for Beijing Inpatient Medical Records. We established a retrospective cohort consisting of 27,665 pregnant women with GDM, and analyzed the association between the occurrence of macrosomia and socio-cultural characteristics of the pregnant women. Results Among the 27,665 pregnant women with GDM, 2,251 (8.1%) gave birth to macrosomia. Pre-pregnancy weight (overweight: RR=2.0, obesity: RR=2.4) and education level (junior middle school and below: RR=1.9, high school and technical secondary school: RR=1.7) were moderately associated with the occurrence of macrosomia. The levels (RR=1.3) anddistricts(RR=1.3) of delivery hospitals were weakly correlated with the occurrence of macrosomia. After adjusting for the related factors, logistic regression analysis showed that pre-pregnancy overweight (OR=1.981, 95%CI:1.796-2.186), obesity (OR=2.446, 95%CI:2.162-2.768) and low education level (compared with master level and above: pregnant women with junior middle school education and below (OR=1.317, 95%CI:1.077-1.611), pregnant women with high school and technical secondary school education (OR=1.247, 95%CI:1.041-1.493)) increased the risk of macrosomia. The risk of macrosomia was increased in the women whodelivered babies in secondary-level hospitals (OR=1.145, 95%CI:1.029-1.273). Conclusion Pre-pregnancy body weight,education level and the level of delivery hospitals are one of the factors influencing macrosomia in pregnant women with GDM; and hence, targeted measures for the primary prevention of macrosomia should be taken.
赵永鲜, 郭默宁, 武明辉, 贾朝霞, 黄丽丽, 王军华. 北京市妊娠期糖尿病孕妇社会文化特征与巨大儿发生的关系研究[J]. 实用预防医学, 2023, 30(5): 532-535.
ZHAO Yong-xian, GUO Mo-ning, WU Ming-hui, JIA Zhao-xia, HUANG Li-li, WANG Jun-hua. Association between socio-cultural characteristics of pregnant women with gestational diabetes mellitus and the occurrence of macrosomia in Beijing. , 2023, 30(5): 532-535.