Abstract：Objective To understand the relationship between dietary inflammatory index (DII) and the occurrence of gestational diabetes mellitus (GDM) as well as the correlation of DII with neutrophil to lymphocyte ratio (NLR), blood glucose and lipid profile. Methods Eighty-two patients with GDM diagnosed in clinic from October 2019 to August 2020 were selected as the observation group, while 82 healthy pregnant women in the same period served as the control group. The DII scores of the two groups were compared, and the correlation between DII during the second trimester of pregnancy and GDM was analyzed by multivariate logistic regression. Pearson correlation analysis was used to analyze the correlation of DII with NLR, fasting blood glucose, total cholesterol and triglyceride. Results The DII score was significantly higher in the GDM group than in the control group, with a statistically significant difference (P<0.01). According to the median DII score, DII was divided into the anti-inflammatory prone group (DII<-0.76) and the pro-inflammatory prone group (DII≥-0.76), and the incidence rates of GDM were 13.41% and 86.58%, respectively, showing statistically significant differences (χ2=4.643, P=0.027). Pearson correlation analysis revealed that the DII level was positively correlated with NLR, fasting blood glucose, total cholesterol and triglyceride, with correlation coefficients of 0.772, 0.879, 0.203 and 0.219, respectively, showing statistically significant differences (P<0.05). The daily intake of pro-inflammatory nutrients was higher in the GDM group than in the control group, whereas the daily intake of anti-inflammatory nutrients was lower in the GDM group than in the control group. Conclusion The DII score can be used as a monitoring index for GDM patients. Reducing DII by adjusting diet structure may decrease the levels of serum NLR, fasting blood glucose, total cholesterol and triglyceride so as to decline the incidence of GDM and its complications.
吴慧, 卢凌鹏, 曹瑞丽, 刘玉红. 妊娠期糖尿病患者膳食炎症指数与中性粒/淋巴细胞比值的相关性研究[J]. 实用预防医学, 2021, 28(9): 1067-1070.
WU Hui, LU Ling-peng, CAO Rui-li, LIU Yu-hong. Correlation between dietary inflammatory index and neutrophil to lymphocyte ratio in patients with gestational diabetes mellitus. , 2021, 28(9): 1067-1070.
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2021, Vol. 28 
