[1] 李平, 陈银苗, 王海亮,等. 儿童手足口病重症病例的危险因素研究现状[J]. 实用预防医学, 2017, 24(2):251-253. [2] 白晶. 丙种球蛋白治疗小儿重型手足口病的疗效观察[J]. 中国地方病防治杂志, 2016,31(9):1070. [3] Arthur Huang KY, Chen MF, Huang YC, et al .Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children[J].Nat Commun, 2017,8(1):762. [4] 甘先民,侯悦媚,黄乙勇,等. 低剂量甲泼尼龙对急性化脓性骨髓炎伴脓毒血症患儿免疫功能及预后的影响[J]. 中华医院感染学杂志,2017,27(14):3327-3330. [5] 中华人民共和国卫生部. 手足口病诊疗指南(2010年版)[J]. 国际呼吸杂志, 2010, 30(24):5. [6] Zhu Z, Ye X, Ku Z, et al .Transcutaneous immunization via rapidly dissolvable microneedles protects against hand-foot-and-mouth disease caused by enterovirus 71[J].J Control Release, 2016,243:291-302. [7] 史晓玲,李昭,王雪君. 甲泼尼龙联合丙种球蛋白对病毒性脑炎重症患儿康复进程及不良反应发生率的影响[J]. 中国地方病防治杂志,2017,32(7):804-806. [8] 万瑞融,杨玉芳,黄振光,等. 我院2010—2013年免疫抑制剂应用分析[J]. 中国药房,2015,26(2):161-164. [9] Lazarenko AA, Alimbarova LM, Mordvintseva EY, et al .Development of the suppository form of human immunoglobulin preparation with high titers of antibodies to herpes simplex virus types 1 and 2 for the treatment of chronic forms of herpetic disease[J].Vopr Virusol, 2017,62(1):36-41. [10] 潘国洪,严军平. 不同剂量肾上腺皮质激素联合抗感染药物治疗儿科重症感染效果[J]. 中国医院药学杂志,2016,36(8):666-669,686. [11] Huang Q, Wang Y, Si C, et al . In terleukin-35 modulates the imbalance between regulatory T cells and T helper 17 cells in enterovirus 71-induced hand, foot, and mouth disease[J].J Interferon Cytokine Res, 2017,37(12):522-530. [12] 王晓宇,成怡冰,宋春兰. 丙种球蛋白对EV71相关重症手足口病患儿热休克蛋白70水平的影响[J]. 广东医学,2016,37(17):2663-2666. [13]Zhu F, Jiang Z, Li HW.Intestinal probiotics in relieving clinical symptoms of severe hand, foot, and mouth disease and potential mechanism analysis[J].Eur Rev Med Pharmacol Sci, 2017,21(18):4214-4218. [14] 李鹏,宋春兰,成怡冰,等. 丙种球蛋白对EV71感染相关肺出血高危儿免疫和细胞因子水平的影响[J]. 实用医学杂志,2016,32(19):3219-3222. [15] Meng J, Yao Z, He Y, et al .Long non-coding RNA expression profiles in different severity EV71-infected hand, foot and mouth disease patients[J].Biochem Biophys Res Commun,2017,493(4):1594-1600. [16] Qu M, Di S, Zhang S, et al .Vitamin D receptor protects glioblastoma A172 cells against Coxsackievirus A16 infection induced cell death in the pathogenesis of hand, foot, and mouth disease[J].Biochem Biophys Res Commun, 2017,493(2):952-956.