Abstract：Objective To understand the main epidemic characteristics and epidemic law of hand, foot and mouth disease (HFMD) in Yiyang City from 2009 to 2020, and to provide a scientific basis for prevention and control work. Methods The data concerning HFMD incidence in Yiyang from 2009 to 2020 were obtained from the Monitoring System for Infectious Diseases in China's Disease Prevention and Control Information System, and the etiological monitoring data were acquired from Yiyang Center for Disease Control and Prevention. Descriptive epidemiological methods and SPSS 20.0 software were used for statistical analysis of the incidence data of HFMD. Results A total of 123,400 cases of HFMD were reported in Yiyang City from 2009 to 2020, including 11 deaths. The incidence rate in 2009 was the lowest (82.36/100,000), while the incidence rate in 2014 was the highest (382.07/100,000). Disease seasonality showed a double-peak pattern, with the main peak occurring in April-July (accounting for 58.26%) and a subsidiary peak appearing in October-November. No statistically significant difference was found in the incidence rates of males and females (χ2=18.200, P=0.077). Most of the cases were children aged 5 years and below, accounting for 96.05%. In terms of occupational distribution, scattered children accounted for 87.30%, and cases of preschoolers for 9.84%. A total of 4,578 samples of HFMD cases were detected from 2010 to 2020, with the pathogen positive rate of 63.54%. The positive constituent ratios of enterovirus 71 (EV71) and coxsackievirus A group 16 (CoxA16) strains were 20.04% and 24.75%, respectively. There were statistically significant differences in the constituent ratios of different virus types in each year (χ2=363.550, P<0.001). The aggregated epidemic mainly occurred in township kindergartens (21 outbreaks). Conclusion HFMD in Yiyang City showed a downward trend since 2014. The key prevention and control groups are children aged 5 years and below, and township nursery institutions are the key prevention and control places. We should pay attention to the changes of dominant pathogens as well as the dominant enteroviruses detected in different years, and adjust prevention and control measures accordingly.
2022, Vol. 29 
