Abstract：Objective The purpose of this study is to probe the relationship between serum uric acid levels and metabolic syndrome and IL-1β among Han, Miao and Buyi nationality adult males in Guizhou. Methods Totally 300 Han male adults , 300 Mao male adults and 200 Buyi male adult were recruited from a hospital's health examina-tion center in minority areas of Guizhou by stratified random sampling method. The general physical and biochemical indicators were measured. Interleukin-1β (IL-1β) is detected by ELISA . Results 1) The difference of detection rate of MS was not statistically significant among the Han, Miao and Buyi, but the detection rate of MS in HUA group were higher than the normal levels of SUA group (P <0.05). Logistic regression results suggested that high TG hyperlipidemia were associated with HUA in the Han population,obesity and high TG hyperlipidemia were associated with HUA in the Miao population,hypertension and high TG hyperlipidemia were associated with HUA in the Buyi population. 2) The levels of IL-1β in the Han, Miao and Buyi were different (P <0.05), and the levels of IL-1β in HUA group were higher than the normal levels of SUA group (P <0.05). The multiple linear regression model also suggested that the levels of SUA have a greater impact on IL-1β among the Han, Miao and Buyi. Conclusion The levels of SUA was closely associated with metabolic syndrome and IL-1β, and there may be a positive role to reduce the development of MS and the variety of metabolic abnormalities by controlled the levels of SUA.
张晓琴, 孙晓红, 贺书琼, 余丽莎, 王显河. 贵州省汉族,苗族和布衣族成年男性血尿酸水平与MS,IL-1β的关系[J]. 实用预防医学, 2016, 23(2): 244-346.
ZHANG Xiao-qin, SUN Xiao-hong, HE Shu-qiong, YU Li-sha, WANG Xian-he. The relationship between serum uric acid levels and metabolic syndrome and IL-1β among Han, Miao and Buyi nationality adult males in Guizhou Province. , 2016, 23(2): 244-346.
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