摘要目的 了解2015—2022年苏州市吴江区慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)死亡率、潜在寿命损失及变化趋势,为开展COPD防治工作提供科学依据。 方法 通过苏州市死因监测系统收集2015—2022年吴江区COPD死亡资料,运用描述流行病学方法,计算COPD粗死亡率、标化死亡率、潜在寿命损失年(potential years of life lost, PYLL)、平均潜在寿命损失年(average years of life lost, AYLL)、潜在寿命损失年率(potential years of life lost rate, PYLLR)、去死因期望寿命(cause eliminated life expectancy, CELE)和期望寿命损失年(years of potential life lost, YLEL);采用年度变化百分比(annual percentage change, APC)分析COPD死亡率与疾病负担变化趋势。 结果 2015—2022年吴江区COPD年均粗死亡率为88.21/10万,年均标化死亡率为32.79/10万,均呈下降趋势,历年男性COPD标化死亡率均高于女性。2015—2022年吴江区COPD死亡率随年龄增长而快速上升,60岁以上居民COPD死亡率随时间呈下降趋势。2015—2022年吴江区因COPD死亡所导致的PYLL总计为1 417.50年,其中男性为990.00年,女性为427.50年。COPD导致的每万人中的男性减寿年数(3.41年)高于女性(1.45年)。各年份PYLL、PYLLR和AYLL均未见明显变化趋势。2015—2022年吴江区COPD YLEL下降0.84岁,其中女性下降1.02岁,男性下降0.67岁。 结论 2015—2022年苏州市吴江区COPD死亡率呈下降趋势,但疾病负担无明显下降,尤其对老年、男性居民的健康威胁较大,应采取有效的干预防治措施,并积极探索COPD管理防控体系的建设。
Abstract:Objective To understand the mortality rate and potential years of life lost (PYLL) due to chronic obstructive pulmonary disease (COPD) and their changing trends among residents in Wujiang District, Suzhou City from 2015 to 2022, and to provide a scientific basis for COPD prevention and treatment. Methods We collected the data about death cases due to COPD from the System for Monitoring Death Causes in Suzhou City from 2015 to 2022. Descriptive epidemiological methods were used to calculate the mortality rate of COPD, PYLL, average years of life lost (AYLL), potential years of life lost rate (PYLLR), cause eliminated life expectancy (CELE) andyears of potential life lost (YLEL). The annual percentage change (APC) was employed to analyze the changing trends of mortality rate and disease burden due to COPD. Results From 2015 to 2022, the average annual crude mortality rate of COPD in Wujiang District was 88.21/100,000, and the average annual standardized mortality rate 32.79/100,000, both showing downward trends. The standardized mortality rate in each year was higher in male COPD patients than in female ones. The mortality rates of COPD in Wujiang District in 2015-2022 increased rapidly with the increasing age, while the mortality rates of COPD in residents aged above 60 years showed a decreasing trend with time. The total PYLL caused by COPD deaths was 1,417.50 years, including 990.00 years for males and 427.50 years for females. The number of COPD-induced years of life lost per 10,000 residents in males (3.41 years) was much longer than that in females (1.45 years). No significant changing trends were found in PYLL, PYLLR and AYLL in each year. The YLEL due to COPD in Wujiang District during 2015-2022 decreased by 0.84 years old, including 1.02 years old for females and 0.67 years old for males. Conclusion The mortality rates of COPD in Wujiang District of Suzhou City during 2015-2022 presented a downward trend, but no obvious decrease was found in the disease burden, especially profound impact on the health of elderly and male residents. It is necessary to take effective intervention and prevention measures and actively pursue the construction of COPD management, prevention and control system.
顾思义, 沈建新, 张荣艳, 杨梅, 彭晓楚. 2015—2022年苏州市吴江区居民慢性阻塞性肺疾病死亡率与疾病负担趋势分析[J]. 实用预防医学, 2024, 31(4): 423-427.
GU Siyi, SHEN Jianxin, ZHANG Rongyan, YANG Mei, PENG Xiaochu. Trends in mortality rate and disease burden of chronic obstructive pulmonary disease among residents in Wujiang District of Suzhou City, 2015-2022. , 2024, 31(4): 423-427.
[1] Celli B, Fabbri L, Criner G, et al. Definition and nomenclature of chronic obstructive pulmonary disease time for its revision[J]. Am J Respir Crit Care Med, 2022, 206(11):1317-1325. [2] Wang C, Xu JY, Yang L, et al. Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health CPH study):a national cross-sectional study[J]. Lancet, 2018, 391(10131):1706-1717. [3] Zhou MG, Wang HD, Zeng XY, et al. Mortality, morbidity, and risk factors in China and its provinces, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017[J]. Lancet, 2019, 394(10204):1145-1158. [4] Stolz D,Mkorombindo T,Schumann DM,et al. Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission[J]. Lancet, 2022, 400(10356):921-972. [5] 健康中国行动推进委员会. 健康中国行动(2019—2030年):总体要求、重大行动及主要指标[J]. 中国循环杂志, 2019, 34(9):846-858. [6] 黄春妍, 王海涛, 陆艳, 等. 1985—2017年江苏省苏州市居民肺癌死亡与潜在减寿趋势分析[J]. 疾病监测, 2018, 33(10):870-874. [7] 李辉章, 杜灵彬. Joinpoint回归模型在肿瘤流行病学时间趋势分析中的应用[J]. 中华预防医学杂志, 2020, 54(8):908-912. [8] 李传苍, 周雅冰, 张梦鸽, 等. 2010—2020年中国居民慢性阻塞性肺疾病死亡趋势分析[J]. 郑州大学学报, 2023, 58(2):269-273. [9] 俞浩, 武鸣, 罗鹏飞, 等. 1990—2017年江苏省居民慢性阻塞性肺疾病的疾病负担分析 [J]. 疾病监测, 2020, 35(6):478-482. [10] 沈腊梅, 陆艳, 黄春妍, 等. 苏州市2011—2020年居民慢性阻塞性肺疾病死亡特征及早死寿命分析[J]. 安徽预防医学杂志, 2023, 29(1):29-32, 38. [11] 薛天怡, 刘世友, 万金豹, 等. 2010—2019年上海市宝山区居民慢性阻塞性肺疾病死亡情况分析[J]. 上海预防医学, 2022, 34(3):256-259. [12] 张艳, 刘庆敏, 付文, 等. 2006—2018年江苏省杭州市居民慢性阻塞性肺疾病死亡率变化趋势分析[J]. 疾病监测, 2020, 35(5):446-450. [13] 白毅,施晓坤,蒋德雄,等. 平昌县农村地区慢阻肺流行病学特征及相关因素分析[J].实用预防医学, 2023, 30(10):1239-1242. [14] Wang S,Ungvari GS,Forester BP,et al. Gender differences in general mental health, smoking, drinking and chronic diseases in older adults in Jilin province, China[J]. Psychiat Res,2017,251:58-62. [15] Wen H, Xie C, Wang L, et al. Difference in long-term trends in COPD mortality between China and the US, 1992-2017: an age-period-cohort analysis[J]. Int J Env Res Pub He, 2019, 16(9):1529. [16] Dumas O, Varraso R, Boggs KM, et al. Association of occupational exposure to disinfectants with incidence of chronic obstructive pulmonary disease among US female nurses[J]. Jama Netw Open, 2019, (2574-3805):e1913563. [17] 杨晓明, 万秋萍, 褚晓婷,等. 2002—2019年上海市静安区居民慢性阻塞性肺疾病疾病负担趋势分析[J]. 中国慢性病预防与控制, 2022, 30(7):549-554. [18] 于晓晶, 徐稳, 宋雅琴. 苏州市空气质量评价分析[J]. 江苏科技信息, 2021, 38(31):72-74. [19] 薛裕钧, 戴静. 2018年与2020年苏州市吴江区≥15岁居民烟草流行状况变化分析[J]. 江苏预防医学, 2022, 33(2):234-236. [20] 吕大伟, 许宏, 王伟俊, 等. 长三角生态绿色一体化发展示范区医疗保障一体化建设的实践与探索[J]. 中国卫生资源, 2021, 24(4):351-355, 365. [21] Sogaard M, Madsen M, Lokke A, et al. Incidence and outcomes of patients hospitalized with COPD exacerbation with and without pneumonia[J]. Int J Chronic Obstr, 2016, 11:455-465. [22] Spannella F, Giulietti F, Cocci G, et al. Acute exacerbation of chronic obstructive pulmonary disease in oldest adults: predictors of in-hospital mortality and need for post-acute care[J]. J Am Med Dir Assoc, 2019, 20(7):893-898. [23] Press VG,Gershon AS,Sciurba FC,et al. Concerns about coronavirus disease-related collateral damage for patients with COPD[J]. Chest, 2020, 158(3):866-868. [24] Reyes FM, Hache-Marliere M, Karamanis D, et al. Assessment of the association of COPD and asthma with in-hospital mortality in patients with COVID-19. A systematic review, meta-analysis, and meta-regression analysis[J].J Clin Med, 2021, 10(10):2087. [25] Munblit D, Bobkova P, Spiridonova E, et al. Incidence and risk factors for persistent symptoms in adults previously hospitalized for COVID-19[J]. Clin Trials, 2021, 51(9):1107-1120. [26] 国家卫生健康委员会疾病预防控制局. 新冠病毒疫苗接种技术指南(第1版)[J]. 中国病毒病杂志, 2021, 11(3):161-162. [27] 赵辉, 白亚娜, 李密, 等. 老年人慢性阻塞性肺疾病住院状况及直接经济负担[J]. 中国老年学杂志, 2016, 36(5):1196-1198. [28] 孙迪, 邵宏涛, 佟斌, 等. 接种肺炎疫苗或流感疫苗对急性加重期慢性阻塞性肺疾病预防效果的研究[J]. 中国初级卫生保健, 2019, 33(10):62-63. [29] 刘笑, 杨楠. 基于补虚法的太极运动对老年人慢性阻塞性肺疾病稳定期患者的影响研究[J]. 世界中西医结合杂志, 2019, 14(11):1584-1587. [30] 周俊男. 综合护理干预对改善老年人慢性阻塞性肺疾病生活质量的观察[J]. 中国医药指南, 2019, 17(19):238-239. [31] 赵原原, 杨念念, 代娟, 等. 武汉市2009—2018年慢性阻塞性肺疾病死亡率变化趋势分析[J]. 中国医院统计, 2021, 28(2):101-104. [32] 陈亦晨, 曲晓滨, 陈华, 等. 2010—2020年上海市浦东新区居民慢性阻塞性肺疾病死亡率及早死概率空间流行病学特征分析[J]. 公共卫生与预防医学, 2023, 34(1):44-48. [33] GBD Chronic Respiratory Disease Collaborators. Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017[J]. Lancet Resp Med, 2020, 8(6):585-596. [34] 苏彦萍, 吴芹,孙晓伟, 等. 2005—2021年北京市通州区慢性阻塞性肺部疾病死亡水平及疾病负担分析[J]. 现代预防医学, 2022, 49(19):3474-3480. [35] 李万华, 李正强, 王爱民, 等. 2012—2021年重庆市大足区慢性呼吸系统疾病死亡率及早死疾病负担趋势变化[J]. 实用预防医学, 2023, 30(2):148-151.