Abstract:Objective To analyze the epidemic features of HIV/AIDS in Chongqing Municipality from 2011 to 2021 so as to provide a reference basis for developing strategies for HIV/AIDS prevention and control. Methods We downloaded the data about reported cases of HIV/AIDS in Chongqing Municipality during 2011-2021 from the Information System for HIV/AIDS Comprehensive Prevention and Treatment of the Chinese Disease Prevention and Control Information System, and then analyzed the cases' distribution features of time, groups and regions. P<0.05 was considered to demonstrate statistically significant differences. Results A total of 71,221 HIV/AIDS cases were cumulatively reported during 2011-2021. The newly reported cases rose from 3,016 cases in 2011 to 8,072 cases in 2021, showing an overall upward trend. Most of the cases were males (75.6%), farmers (37.3%) and people with primary education (34.8%). The majority of the cases were aged 50 years and above (50.5%), and the proportion of cases aged 50 years and above showed an increasing trend year by year (χ2trend=3,377.030, P=0.000). 83.1% of the caseswere concentrated in the main downtown areas, and 78.8% were infected by heterosexual sex. Most of the cases were detected in medical institutions, accounting for 57.6%. Conclusion The epidemic of HIV/AIDS in Chongqing Municipality from 2011 to 2021 showed an overall upward trend. The situation of prevention and treatment in people aged 50 years and above is grim, and sexual transmission is the main route of transmission currently. Interventions for sexual transmission in key populations need to be further enhanced.