Abstract:Objective To explore the therapeutic effect of nutritional support combined with functional training on patients with chronic obstructive pulmonary disease (COPD) by a meta-analysis. Methods We searched PubMed, Cochrane Library, Web of Science, CNKI, Wanfang and VIP databases to collect randomized controlled trials (RCTs) on the effect of nutritional support combined with functional training on rehabilitation of COPD patients with the help of EBM AI-Reviewer. The search period was set from January 2000 to March 2022, and the obtained data were processed using RevMan 5.3 software. Results A total of 10 papers were enrolled into the analysis, including 961 subjects (477 subjects in the experimental group and 484 subjects in the control group). Meta-analysis results showed that nutritional support combined with functional training significantly improved the COPD patients' forced expiratory volume in one second (FEV1) (MD=0.34 L, 95%CI:0.13-0.55), percentage of predicted forced expiratory volume in 1 second (FEV1% pred) (MD=4.24%, 95%CI:2.53-5.95), forced vital capacity (FVC) (MD=0.33 L, 95%CI:0.12-0.54), FEV1/FVC (MD=2.35%, 95%CI:1.63-3.07), albumin (ALB) (MD=2.68 g/L, 95%CI:1.98-3.38), hemoglobin (Hb) (MD=13.93 g/L, 95%CI:10.74-17.13),and scores ofSt. George's Respiratory Questionnaire (SGRQ, MD=11.97, 95%CI:9.57-14.36) and COPD assessment test (CAT, MD=2.99, 95%CI:2.41-3.56). Conclusion Nutritional support combined with functional training improves the COPD patients' lung function, nutritional level and quality of survival, which is suitable for their clinical rehabilitation.
贾娟, 薛世民. 营养支持联合功能训练对慢性阻塞性肺疾病患者的康复影响:一项荟萃分析[J]. 实用预防医学, 2022, 29(12): 1459-1463.
JIA Juan, XUE Shi-min. Effects of nutritional support combined with functional training on recovery in patients with chronic obstructive pulmonary disease: a meta-analysis. , 2022, 29(12): 1459-1463.