Monitoring and analysis of peripheral blood cell count and lymphocyte micronucleus among interventional workers with radiation exposure in Shenzhen City
LIU Zheng-yu, GAO Chao-xian, LI Li-mei, ZHANG Yi, ZHANG Zhi-min, LIN Da-feng
Institute of Pathology and Toxicology, Shenzhen Prevention and Treatment Center for Occupational Diseases, Shenzhen, Guangdong 518020, China
Abstract：Objective To monitor and analyze the influence of long-term ionizing radiation exposure on peripheral blood cell count and lymphocyte micronucleus among interventional radiation workers in Shenzhen City, and to provide a basis foroccupational health management of interventional workers with radiation exposure. Methods We recruited 591 radiation workers from 15 first-class grade A hospitals in Shenzhen City from 2017 to 2018, and all of them underwent health check-ups in Shenzhen Prevention and Treatment Center for Occupational Diseases. Among them, 304 interventional radiation workers were selected into the interventional radiation group, and 287 X-ray imaging diagnosis workers served as the general X-ray group at the same time. We compared and analyzed their personal external radiation exposure dose, peripheral blood cell counts and lymphocyte micronucleus rate and conversion rate. Results The average age of the interventional radiation group was 37.0 (32.0, 45.0) years, the males accounted for 62.17%, and the annual effective dose per-capital was 0.07 (0.04, 0.21) mSv. The average age of the general X-ray group was 36.0 (30.0, 44.0) years, the males accounted for 55.40%, and the annual effective dose per-capital was 0.03 (0.03, 0.05) mSv. There was a statistically significant difference in the annual effective dose per-capital between the two groups (W=21,676, P=0.000). In the total white blood cell count, lymphocyte percentage, neutrophil percentage, and lymphocyte micronucleus rate, the results showed statistically significant differences for the comparison between the two groups (all P<0.05). With the increase of radiation working years, the lymphocyte micronucleus rate and abnormal detection rate in the interventional radiation group both increased, showing statistically significant differences (both P<0.05), but the changes of bloodcell count in the interventional radiation group were not statistically significant. Conclusion The radiation dose of the interventional radiation workers in Shenzhen City is relatively low, but their lymphocyte micronucleus rate and abnormal detection rate show significantly increasing trends with radiation working years. It is necessary to further enhance the interventional radiation workers’ occupational health management and improve their personal protection awareness so as to lower the level of radiation damage to the minimum and ensure their health and occupational safety.
2021, Vol. 28 
