Bidirectional screening and treatment results of Mycobecterium tuberculosis/humanimmunodeficiency virus co-infection in rural areas of Nanning city, 2014-2017
HE Bo1, NONG Li-ping1, LI Huo-jia2, LIN Qian1, LI Si-si1, LI Shu1, CHEN Wen-cai1, CEN Ping1, YAO Min1
1.Nanning Municipal Center for Disease Control and Prevention, Nanning, Guangxi 530023, China; 2.Health Supervision Institute of Guangxi Zhuang Autonomous Region, Nanning, Guangxi 530021, China
Abstract：Objective To investigate the status of bidirectional screening and treatment of Mycobecterium tuberculosis (MTB)/human immunodeficiency virus (HIV) co-infection in rural areas of Nanning city from 2014 to 2017, and to provide a scientific basis for prevention and therapy of MTB/HIV co-infection. Methods Primary screening of HIV antibody assay was carried out in newly registered tuberculosis (TB) patients in outpatient departments of TB control and treatment institutions in Nanning city, and the positive cases were verified. TB-suspicious symptom screening was performed in HIV/AIDS patients who were alive and were followed-up in HIV/AIDS prevention and treatment institutions, then the patients were referred to local TB control and treatment institutions for sputum smears and chest imaging examination. We analyzed the data concerning bidirectional screening and treatment of MTB/HIV co-infection in 4 counties of Nanning city in 2014-2017. Results The total detection rate of HIV antibody in newly registered TB patients in rural areas of Nanning city in 2014-2017 was 87.16%, the detection rates in 2014-2017 showed statistically significant differences (χ2=33.838, P<0.001) as well as an upward tendency year by year (χ2tendency=32.647, P<0.001). The positive rate of HIV antibody was 0.68%, without a statistically significant difference in different years (χ2=5.481, P>0.05). The rate of TB screening (χ2=248.244, P<0.01) and the positive rate of TB (χ2=78.027, P<0.001) in HIV/AIDS patients were fluctuant, and the above-mentioned rates in 2016 were the highest (96.95%, 3.50%). Most of patients with MTB/HIV con-infection were found in MSH county. The comprehensive treatment rate in patients with MTB/HIV con-infection was 54.25%, and the rates in 2015-2017 increased year by year (χ2=26.241, P<0.001). The success rate of anti-TB treatment was 39.16%. Conclusions The work regarding bidirectional screening, prevention and treatment of MTB/HIV co-infection in Nanning city in 2014-2017 was gradually improved, but the epidemic of MTB/HIV co-infection in some areas was serious. It is necessary to further enhance and improve TB and HIV/AIDS comprehensive service mechanism so as to promote accessibility of patients’ diagnosis and treatment, therapy rate and therapeutic efficacy and effectively control the epidemic of MTB/HIV co-infection.
何波, 农丽萍, 黎火佳, 林倩, 李斯斯, 黎舒, 陈文才, 岑平, 姚敏. 2014—2017年南宁市农村地区MTB/HIV感染双向筛查与治疗结果分析[J]. 实用预防医学, 2019, 26(12): 1416-1420.
HE Bo, NONG Li-ping, LI Huo-jia, LIN Qian, LI Si-si, LI Shu, CHEN Wen-cai, CEN Ping, YAO Min. Bidirectional screening and treatment results of Mycobecterium tuberculosis/humanimmunodeficiency virus co-infection in rural areas of Nanning city, 2014-2017. , 2019, 26(12): 1416-1420.
2019, Vol. 26 
