Abstract：Objective To explore the risk factors related to preterm labor in Shenzhen city, and to provide references for preventing preterm birth. Methods The parturients and newborns who delivered in a maternal and child health care hospital in Shenzhen city from January 1 to December 31 in 2015 were selected as the research subjects. The mothers of 200 newborns born at 28 and less than 37 weeks’ gestation were taken as the case group, while the mothers of 200 newborns born at 37 and 42 weeks’ gestation were considered as the control group. The daily average concentration of air pollutants, including SO2, NO2, PM10, PM2.5, CO and O3, in Shenzhen city from January 1, 2014 to December 31, 2015 was collected. Logistic regression model was used to analyze the factors influencing preterm birth. Resultss The quality of air in Shenzhen city from 2014 to 2015 was good. Statistically significant differences were found in the exposure air concentration of SO2 in early pregnancy ((10.00±5.10)μg/m3vs. (8.66±5.03) μg/m3), the exposure air concentration of NO2 in early pregnancy ((38.23±15.98)μg/m3vs. (35.33±15.01)μg/m3), the exposure air concentration of PM10 in late pregnancy ((54.26±28.00)μg/m3vs. (51.39±27.92)μg/m3) and the exposure air concentration of PM2.5 in late pregnancy ((32.96±19.20) μg/m3vs. (30.11±18.36) μg/m3) between the case group and the control group (all P<0.05). There were statistically significant differences in the maternal age ((29.2±5.4) years old vs. (27.6±6.0) years old) and the proportion of mothers with a family history of preterm labor (38.5% vs. 26.5%) and the proportion of mothers with college education and above (62.5% vs. 73.5%) between the case group and the control group (all P<0.05). Multivariate logistic regression analysis showed that maternal age(OR=1.009, 95%CI:1.002-1.018) , having a family history of preterm birth (OR=1.308,95%CI:1.019-1.714), PM2.5 in late pregnancy (OR=1.387, 95%CI:1.112-1.579), PM10 in late pregnancy (OR=1.267, 95%CI:1.108-1.531), SO2 in early pregnancy (OR=1.118, 95%CI:1.009-1.329) and NO2 in early pregnancy (OR=1.106, 95%CI:1.009-1.273) affected preterm birth. Conclusions Air pollutants in Shenzhen city, such as SO2, NO2, PM10 and PM2.5, maternal age and having a family history of premature birth are associated with preterm birth.
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2019, Vol. 26 
