Research progress on the effect of maternal pre-pregnancy obesity on neuropsychological development of offspring
NIU Xin, ZHU Wan-qiu, BAI Ying-long, JIA Li-hong, ZHAI Ling-ling, SUN Qi, WEI Wei
Department of Child and Adolescent Health and Maternal and Child Health Care, School of Public Health,China Medical University, Shenyang, Liaoning 110122, China
Abstract：Obesity in adult women is a global public health problem. Maternal pre-pregnancy obesity may have adverse effects on cognitive function and mental development of offspring and increase the risk of offspring’s behavioral problems, attention deficit and hyperactivity disorder (ADHD) and autism spectrum disorders (ASD). The specific mechanism of maternal pre-pregnancy obesity on the neuropsychological development of offspring is not clear, brain-derived neurotrophic factor (BDNF), the changes in offspring’s brain metabolism and inflammation may be involved in it. This article briefly reviews the effect of maternal pre-pregnancy obesity on the neuropsychological development of offspring and the related mechanism, and calls on relevant departments and medical staff to actively prevent maternal pre-pregnancy obesity so as to promote the healthy development of offspring.
牛欣, 朱婉秋, 白英龙, 贾丽红, 翟玲玲, 孙琦, 魏薇. 孕前母亲肥胖对子代神经心理发育影响研究进展[J]. 实用预防医学, 2019, 26(9): 1150-1153.
NIU Xin, ZHU Wan-qiu, BAI Ying-long, JIA Li-hong, ZHAI Ling-ling, SUN Qi, WEI Wei. Research progress on the effect of maternal pre-pregnancy obesity on neuropsychological development of offspring. , 2019, 26(9): 1150-1153.
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2019, Vol. 26 
