Abstract:Objective To describe the epidemiological features of viral hepatitis C in Jilin Province from 2008 to 2017,to explore the changing trend of incidence of viral hepatitis C in Jilin Province,and to provide a scientific basis for its prevention and control. Methods We made a descriptive epidemiological analysis of viral hepatitis C in Jilin Province during 2008-2017 based on the surveillance data from China Disease Prevention and Control Information System.Results The incidence rate of viral hepatitis C in Jilin Province during 2008-2017 increased from 21.18/100,000 in 2008 to 33.06/100,000 in 2011, and then decreased year by year since 2012. The number of cases reported in Songyuan City was the largest, and the average annual incidence rate in Yanbian City was found to be the highest (47.12/100,000). The male-to-female ratio was 1.23∶1. 91.25% of the patients were 40 years old and above. Farmers accounted for the largest proportion of the patients (38.06%).Conclusions The reported incidence rate of hepatitis C in Jilin Province showed a downward trend since 2012. Oral direct-acting antiviral agents(DAA) have now been put on the market in China. Medical resources should be actively coordinated to carry out treatment work in areas with high prevalence of hepatitis C so as to effectively improve the cure rate of hepatitis C.
[1] World Health Organization. Global hepatitis report 2017[R]. Geneva: WHO, 2017:1-20. [2] 孙海泉,肖革新,郭莹,等.中国2008-2012年丙肝流行规律及空间聚集性分析[J].中国公共卫生,2014,30(3):286-289. [3] Wang L, Xing J, Chen F, et al. Spatial analysis on hepatitis C virus infection in mainland China: from 2005 to 2011[J]. PLoS One, 2014, 9(10): e110861. [4] 连巧龄,吴韶彬,陈亮.2005-2015年福建省丙型病毒性肝炎流行特征分析[J].中国艾滋病性病,2017,23(1):56-59. [5] 徐春华,刘瑾,宋涛.2005-2016年商丘市丙型肝炎流行特征分析[J].河南预防医学杂志,2017,28(10):796-798. [6] 陈国翠,谢旭,陈伟红,等.2010-2014年深圳市乙型和丙型病毒性肝炎流行特征分析[J].实用预防医学,2017,24(7):810-813. [7] 卢欣荣,赵庆龙.吉林省医疗机构丙型肝炎病毒检测能力调查[J].中国艾滋病性病,2017,23(7):666-668. [8] 郭建华,邓立权,徐常喜.吉林省2009-2011年病毒性丙型肝炎重复报告情况分析[J].中国卫生工程学,2015,14(1):50-51,54. [9] 卢欣荣,邓立权,栾博,等.吉林省延边州丙型肝炎防控项目工作经验[J].慢性病学杂志,2013,14(5):392-393. [10] Piao HX, Yang AT, Sun YM, et al. Increasing newly diagnosed rate and changing risk factors of HCV in Yanbian Prefecture, a high endemic area in China[J]. PLoS One, 2014, 9(1):e86190. [11] 黄飚,邓立权,卢欣荣.延边州人群丙肝感染影响因素分析[J].实用预防医学,2013,20(5):556-557. [12] Xu H, Yu G, Sun H, et al. Use of parenteral caffeinum natrio-benzoicum: an underestimated risk factor for HCV transmission in China[J]. BMC Public Health, 2015, 15(1):928. [13] 闻静,高榆,丁国伟,等.中国5省9家医院就诊人群中丙型肝炎患者诊疗现状研究[J].中国艾滋病性病,2018,24(6):581-584. [14] 宋金辉,吕硕.吉林省2011-2015年丙肝相关肝硬化、肝癌回顾性调查研究[J].世界最新医学信息文摘,2017,17(A3):243,246. [15] 屈慧新,王玉泽,王彩霞,等.新型抗丙型肝炎病毒药索非布韦的研究进展[J].沈阳药科大学学报,2016,33(4):334-338.