Abstract:Objective To analyze the results of HIV viral load after receiving antiretroviral therapy and related influencing factors in HIV infectors/AIDS patients (hereinafter to be referred as HIV/AIDS patients) in Shaanxi Province. Methods The viral load of HIV was detected in 1,046 HIV/AIDS patients who underwent antiretroviral therapy for more than six months, and the viral load results and related influencing factors were analyzed combined with their epidemiological data. Results Among the 1,046 HIV/AIDS patients, patients with HIV viral load ≥ 1,000 copies/ml, 50-999 copies/ml and <50 copies/ml and patients reported as TND (target not detected) accounted for 9.6% (100/1,046), 9.1% (95/1,046), 25.4% (266/1,046) and 55.9% (585/1,046) respectively. Univariate analysis showed that there were statistically significant differences in the ethnic group (P<0.05), educational background (χ2=10.901, P<0.05), route of infection (χ2=14.286, P<0.05) between the group of HIV viral load < 1,000 copies/ml and the group of HIV viral load ≥ 1,000 copies/ml. Multivariate logistic regression analysis showed that college and above educational background was the protective factor for viral load ≥ 1,000 copies/ml (OR=0.344, 95%CI:0.121-0.979), while injection drug use was the risk factor for viral load ≥1,000 copies/ml (OR=5.237, 95%CI:1.272-21.556). Conclusions Antiretroviral therapy for HIV/AIDS patients in Shaanxi Province is characterized with good clinical effect, but it is still necessary to improve the patients’ treatment compliance and reduce the virus suppression failure.
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