Abstract:Objective To depict the characteristics of deaths caused by malignant tumors and their changing tendency in urban residents of Xuzhou City from 1989 to 2013 so as to provide scientific basis for studying tumor prevention and treatment strategy and evaluating its effect. Methods We analyzed the mortality rates and the age-standardized mortality rates of malignant tumors, proportion of deaths and rank of death causes in urban residents of Xuzhou City during 1989-2013. Joinpoint regression analysis was performed to obtain the average annual percentage changes (AAPC) in the mortality rates and the age-standardized mortality rates. Results The crude mortality rate and the age-standardized mortality rate of malignant tumors in urban residents of Xuzhou City during 1989-2013 were 119.56/100,000 and 88.48/100,000 respectively. Both mortality rates were higher in males than in females (150.65/100,000 vs. 85.32/100,000, χ2= 2659.86,P<0.01 and 122.51/100,000 vs. 57.85/100,000, χ2=3,394.82, P<0.01). The crude mortality rate increased with an annual percentage change of 0.5% during 1989-2013, while the age-standardized mortality rates decreased with an annual percentage change of 1.8%. The top five death causes of malignant tumors were lung cancer, liver cancer, stomach cancer, esophageal cancer and colorectal cancer, accounting for 73.18% of all the deaths. The mortalities of the main malignant tumors were all significantly higher in males than in females (all P<0.05), except for breast cancer and cervical cancer. The age-specific mortality rate of malignant tumors increased with the age since 30 years old. Conclusions Malignant tumors were the leading causes of deaths in urban residents of Xuzhou City in 1989-2013. Aging of population was the major cause of the increase of mortality rates of malignant tumors. It is necessary to strengthen comprehensive prevention and treatment, actively promote health education and healthy life styles so as to decline the incidence and death risk of malignant tumors.