Abstract:Objective To investigate the serotyping and drug resistance of Vibrio parahaemolyticus in Huzhou City during 2013-2015 so as to prevent foodborne diseases caused by Vibrio parahaemolyticus and provide a basis for guiding rational clinical therapy. Methods We collected Vibrio parahaemolyticus isolates from the food poisoning cases and the monitored aquatic products in Huzhou City form 2013 to 2015. VITEK2 automated microbial analysis system was used for drug resistance testing, and slide agglutination test for serological testing. Results Among 206 strains of Vibrio parahaemolyticus, 7 serogroups and 25 serotypes were detected. O3: K6 was the dominant strain isolated from the food poisoning cases, accounting for 64.3%. The serotypes of the isolates from the aquatic products showed a scattered distribution. The drug resistance to ampicillin and amoxicillin was both higher than 95%, and to cefazolin was 66.7% and 55.5% respectively. All the 206 strains of Vibrio parahaemolyticus were sensitive to imipenem, aztreonam, levofloxacin, nalidixic acid, macrodantin, ciprofloxacin, tobramycin, sulfamethoxazole and chloromycetin. Conclusions The serogroups of Vibrio parahaemolyticus strains isolated from the aquatic products in Huzhou City present diversification; moreover, there exists a certain degree of drug resistance.