Abstract：Objective To learn the subgenotypes of human papillomavirus(HPV) from the infected females in Gansu province as well as their age and regional distribution. MethodsSamples were collected from 7,318 females who consulted in the Cervical Disease Treatment Center of Lanzhou Military Authority, the Department of Pathology of Command Hospital of Lanzhou Military Area, the Obstetrics and Gynecology Outpatient in Lanzhou University Second Hospital, the Obstetrics and Gynecology Outpatient in The People’s Hospital of Chengxian and the Department of Pathology in The People’s Hospital of Longnan from May, 2010 to July , 2012. The subgenotypes of the HPV detected in the samples were determined by cape flow-through hybridization and gene chip technology. ResultsThe infection rate of HPV in females in Gansu Province was 19.9%(1,452/7,318). The infection rate of high-risk HPV (HR-HPV) was 14.78% and that of the low-risk HPV (LR-HPV) was 3.38%. From the 1,452 HPV-infected samples, HPV16 was found to be the main pathogenic subtype, accounting for 28.58%. Single infection accounted for 81.82% and multiple infection accounted for 18.18%. As for age, the females aged 50 years and above had the highest HPV infection rate ( 24.24%). As for region, Longnan was the place with the highest infection rate (30.97%). ConclusionsGansu is a high-incidence area of HPV. It is of top priority to screen and prevent cervical cancer among females in this area.
杜宏, 索兰草, 刘红贤, 王强, 刘斌, 简启亮, 黄山, 张文华, 王芳. 甘肃地区女性宫颈HPV感染现状[J]. 实用预防医学, 2015, 22(1): 17-19.
DU Hong, SUO Lan-cao, LIU Hong-xian, WANG Qiang, LIU Bin, JIAN Qi-liang, HUANG Shan, ZHANG Wen-hua, WANG Fang. Current situation of cervical HPV infection in females in Gansu Province. , 2015, 22(1): 17-19.
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