Abstract：Objective To know the levels and relationship of measles antibody in newborns with their mothers, and the duration of maternal delivered measles antibodies in infants. Methods a total of 109 mother newborn pairs’ serum sample and 87 three month, 79 five month, 63 seven month infants’ serum samples were collected in Luohu to test the measles antibody level with ELISA. Results the geometric mean concentration (GMC) of maternal measles antibody was 646.28mIU/ml, and GMC of neonatal measles antibody was 1001.39mIU/ml , which was 1.55 times more than the geometric mean concentration of maternal measles antibody（paired t =9.368,P<0.001); the GMC decreased to 161.63mIU/ml,125.61mIU/ml and 112.91mIU/ml in 3,5 and 7 month infants respectively. Both positive rate and protective rate of measles antibodies were significantly lower in mothers than in newborns, ( χ2=39.176,P<0.001; χ2=35.821,P<0.001). and decreased monthly after birth(χ2positive=115.618, P<0.001;χ2protective=109.441, P<0.001). 64.22% of all pairs shared the same degree of antibody level. Maternal logarithmic concentration of measles antibody was positively correlated with logarithmic concentration of newborns, 3, 5 and 7 month babies,the coefficients of correlation were 0.897, 0.768, 0.574, 0.257 respectively. Conclusion maternal measles antibody level was the key factor affecting newborn’s antibody level; enhancing measles vaccine immunization for women of child-bearing age is an important method to control the onset of measles in infants.
马茂, 刘卫民, 杨洁, 林喜乐, 付丹凤, 何莲娇. 深圳市罗湖区109对母婴配对麻疹母传抗体水平研究[J]. 实用预防医学, 2016, 23(5): 561-564.
MA Mao, LIU Wei-min, YANG Jie, Lin Xi-le, FU Dan-feng, HE Lian-jiao. study on the maternal delivered measles antibody in 109 maternal infant pairs in Luohu district Shenzhen. , 2016, 23(5): 561-564.
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2016, Vol. 23 
