Abstract:Objective To investigate the control status of patients with type 2 diabetes mellitus (T2DM) in Changshu City and to preliminarily explore the influencing factors of blood glucose control among the patients, so as to provide references for adopting effective countermeasures. Methods A questionnaire survey on diabetes mellitus was conducted among 10,246 T2DM patients selected by multi-stage cluster sampling method from those covered by basic public health services in Changshu City from October 2013 to February 2014. Physical and biochemical examinations including fasting blood glucose, hemoglobin A1C (HbA1c), triglyceride (TG) and high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) were performed. Unconditional logistic regression analysis was performed with HbA1c as the dependent variable. The influencing factors with P<0.1 in the single factor unconditional logistic regression analysis was included into the multi-factor analysis, and stepwise regression method was used to perform multi-factor unconditional logistic regression analysis to explore the factors influencing blood glucose. Results The complete data about 10,238 T2DM patients were obtained. The mean HbA1c concentration of the patients was (7.6±1.6)%, and 59.2% of the patients had HbA1c ≥7.00%. The single factor unconditional logistic regression analysis showed that gender, age, residence, education background, BMI, waistline, serum lipid, smoking and drinking significantly influnced the HbAlc level (P<0.01). The multi-factor unconditional logistic regression analysis showed that residence (countryside/city OR=1.359,95%CI:1.252~1.475, P<0.001), smoking(OR=1.474,95%CI:1.327~1.638, P<0.001), dyslipidemia(OR=1.240,95%CI:1.143~1.346, P<0.001), waist (central obesity OR=1.294, 95%CI:1.192~1.405, P<0.001)and educational background (without receiving formal education as the reference: primary school OR=0.825,95%CI:0.741~0.920, P<0.001; junior middle school and above OR=0.895,95%CI:0.808~0.991, P<0.001)were the independent influencing factors of glycemic control. Conclusions The glycemic control of the patients with T2DM in Changshu City is not optimistic. It is influenced by residence, smoking, dyslipidemia, central obesity and educational background. It is necessary to actively carry out comprehensive measures to control blood glucose and the occurrence of diabetes complications.