Abstract：Objective To investigate rubella antibody levels of children and teenagers in Fuling District, Chongqing Municipality so as to provide data support for formulating rubella prevention and control measures. Methods Cluster random sampling method was used to select children and teenagers aged between 2 and 15 years in Fuling District, Chongqing Municipality. Whole blood samples were collected, and ELISA was employed to detect rubella IgG antibody. Result A total of 3,230 blood samples were detected, and 2,867 were positive for rubella IgG antibody, with the positive rate of 88.76%. The positive rates of rubella IgG antibody in 5 monitoring sites with different azimuths (including east, west, north, south and central areas) were 94.63%, 89.47%, 77.95%, 93.77% and 88.11% respectively. There were statistically significant differences in the positive rate of rubella IgG antibody among different monitoring sites (χ2=114.048, P<0.05) as well as between unban areas and townships (90.91% vs. 87.32%; χ2=10.032, P<0.05). The positive rates of rubella IgG antibody in children aged 2-5 years and 6-10 years and children/teenagers aged 11-15 years were 91.25%, 87.74% and 87.38% respectively, with statistically significant differences (χ2=9.712, P<0.05). The positive rates of rubella IgG antibody in males and females were 89.21% and 88.29% respectively, but no statistically significant difference was found between two genders (χ2=0.686, P>0.05). Conclusions Children and teenagers with successful vaccination of rubella virus vaccine or rubella virus IgG antibody level higher than the minimum protection titer in Fooling District, Chongqing Municipality account for 88.76%, which indicates that they maintain a high level of rubella antibody. But it is still necessary to intensify the supplementary immunization, promote the routine immunization of rubella virus vaccine and simultaneously further improve the immunization coverage rate of villages and towns.
张仁平, 田应桥, 杨德明, 曹勇, 康小丽, 杨帆. 重庆市涪陵区儿童少年风疹抗体监测分析[J]. 实用预防医学, 2016, 23(9): 1081-1083.
ZHANG Ren-ping, TIAN Ying-qiao, YANG De-ming, CAO Yong, KANG Xiao-li, YANG Fan. Surveillance on rubella antibody levels in children andadolescents in Fuling District, Chongqing Municipality. , 2016, 23(9): 1081-1083.
2016, Vol. 23 
