Hemoglobin A1c level in the middle-aged and elderly community residents and its correlations with metabolic syndrome and other metabolic disorders in Zhengzhou City, 2011
WANG Li*, WANG Qing-zhu, QIN Gui-jun, ZHAO Yan-yan, ZHANG Ying-hui, MA Xiao-jun, MA Xiao-kun, REN Gao-fei
*Department of Endocrinology, People's Hospital of Anyang, Anyang, Henan 455000, China
Abstract:Objective To investigate hemoglobin A1c (HbA1c) level in the middle-aged and elderly community residents and its correlations with metabolic syndrome (MS) and other metabolic disorders. Methods Questionnaire survey, physical examination and laboratory examination were conducted in 8,237 middle-aged and elderly residents in 4 communities in Zhengzhou City in July, 2011. The prevalence of MS and various metabolic disorders were investigated for groups with HbA1c <5.7%, 5.7%~ and 6.5%~. The correlations of HbA1c with MS and various metabolic disorders were explored by Pearson correlation anlysis. Results The HbA1c level of the middle-aged and elderly residents was high. The prevalence of MS and various metabolic disorders rised with HbA1c level. When HbA1c was 6.5% or higher, the prevalence of MS, central obesity, high triglyceride (H-TG) and low high density lipoprotein cholesterol (HDL-C) was 81.7%, 78.0%, 50.8% and 58.0% respectively. HbA1c was negatively correlated with HDL-C, but positively correlated with waist circumference (WC), body mass index (BMI), diastolic blood pressure (DBP), total cholesterol (TC), TG, low density lipoprotein cholesterol (LDL-C), 2-hour plasma glucose in the oral glucose tolerance test (2hPG) . Conclusions The HbA1c level of the middle-aged and elderly community residents in Zhengzhou City in 2011 is high. When HbA1c is 6.5% or higher, the prevalence of MS and various metabolic disorders increases, and there are strong correlations between HbA1c and MS and various metabolic disorders.
汪丽, 王庆祝, 秦贵军, 赵艳艳, 张颖辉, 马晓君, 马笑堃, 任高飞. 2011年郑州市中老年人糖化血红蛋白水平及与代谢综合征及各种代谢紊乱的相关性[J]. 实用预防医学, 2016, 23(10): 1229-1231.
WANG Li, WANG Qing-zhu, QIN Gui-jun, ZHAO Yan-yan, ZHANG Ying-hui, MA Xiao-jun, MA Xiao-kun, REN Gao-fei. Hemoglobin A1c level in the middle-aged and elderly community residents and its correlations with metabolic syndrome and other metabolic disorders in Zhengzhou City, 2011. , 2016, 23(10): 1229-1231.
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