Pathogenic characteristics and traceability of a water-borne bacillary dysentery outbreak
QIN Di, JIA Hua-yun, DENG Zhi-hong, HE Zi-xiang, XIA Xin, Gao Li-dong, CAI Liang, ZHANG Hong
Hunan Provincial Key Laboratory of Microbial Molecular Biology, Hunan Provincial Center for Disease Control and Prevention, Changsha,Hunan 410005, China
Abstract：Objective To trace the source of a waterborne bacterial dysentery form a school outbreak and to analyze the etiological characteristics and genetic correlation between the patient strains and the isolated environmental strains. Methods All the 29 Shigella bacteria strains isolated from patients and well water were subject to isolation and identification, serotyping and drug sensitive test. Electrophoresis patterns were obtained by pulsed field gel electrophoresis (PFGE), and then subject to cluster analysis by BioNumerics to study the correlation among the strains. Results All the 29 isolates were Shigella sonnei Phase Ⅰ, and 96.55% isolates produced extended spectrum β-lactamases. Three kinds of PFGE patterns were obtained, with similar rates between 72.8%-100%. The 25 isolates from patients and 2 from well water were 100% homologous. Conclusions Based on the laboratory Results and epidemiological investigation, it is a water-borne bacillary dysentery outbreak caused by drinking or using Shigella sonnei contaminated well water.
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2016, Vol. 23 
