Abstract：Chlamydia trachomatis (Ct) is a common obligate intracellular parasitic microorganism. It can cause female cervicitis, salpingitis, pelvic inflammation, endometritis and other diseases, and is also one of the most common sexually transmitted pathogens. So far, there is no specific Ct vaccine to prevent its transmission. At present, the pathogenic mechanism of Ct has not been fully understood, but it has been cloned and verified, including heat shock protein, main outer membrane protein, chlamydial secretory protein, plasmid protein and some newly-discovered possible virulence proteins due to the rapid development of molecular biology, bioinformatics and biophysics. This study introduces the research progress on these virulence factors so as to provide references for prevention and control of Ct-induced diseases.
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2023, Vol. 30 
