Abstract:Objective To establish an analytical method for rapid determination of 50 volatile organic compounds in workplace air. Methods Through the optimization of thermal desorption parameters, we analyzed 50 volatile organic compounds in workplace air by the optimized thermal desorption-cold trap-gas chromatography-mass spectrometry method, verified theperformance indexes of the method, and applied them to the detection of actual samples. Results The target compounds had a good linear relationship in the range of 5-200 ng, with the correlation coefficient r > 0.995. The method detection limits were 0.02-0.65 μg/m3 (based on the sampling volume of 2 L). The recovery rates were in the range of 81.3%-105.0%, and the relative standard deviation ranged between 1.3% and 9.8% (n=7). The method was used to collect and detect the air in two sections of a factory, and 9 target compounds were detected, with the concentration range of 2.2-50.7 mg/m3. Conclusion The method is simple, good linear, highly sensitive, precise and accurate, which can realize the rapid detection of 50 volatile organic compounds in workplace air.
唐华民, 席强, 卢文婷. 热脱附-冷阱捕集-气相色谱-质谱法测定工作场所空气中50种挥发性有机物[J]. 实用预防医学, 2023, 30(3): 321-324.
TANG Hua-min, XI Qiang, LU Wen-ting. Determination of 50 volatile organic compounds in workplace air by gas chromatography-mass spectrometry with thermal desorption and cold trap. , 2023, 30(3): 321-324.
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