Determination of pentachlorophenol in chicken and pork by QuEChERS-mixed adsorbent dispersive solid phase extraction with gas chromatography-triple quadrupole mass spectrometry
XU Ling-zhen, HU Ming-you, YAO Jian-hua
Huzhou Municipal Center for Disease Control and Prevention, Huzhou, Zhejiang 313000, China
Abstract：Objective To establish a method for the determination of pentachlorophenol in chicken and pork usingQuEChERS-mixed adsorbent dispersive solid phase extraction with gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS). Methods Five percent trichloroacetic acid was added to samples to precipitate proteins, then acetonitrile and QuEChERS extraction package were added to extract. Mixed adsorbents were used to disperse solid phase extraction andpurification, and derived with acetic anhydride pyridine solution. GC-MS/MS was applied to determination, and2,4,6-tribromophenol was selected as internal standard for quantification. Results The pentachlorophenol measured in this experiment had a good linear relationship (r>0.999). The limit of detection (S/n=3) was 0.01μg/kg, and the limit of quantification 0.03μg/kg. The recoveries ranged from 89.8% to 115.2%, and the relative standard deviation from 1.6% to 11.3%. Conclusion The method is simple in operation, accurate in quantification, good in reproducibility and precision, and of low detection limit. It is suitable for the detection of pentachlorophenol in chicken and pork.
徐玲珍, 胡明友, 姚建花. QuEChERS-混合型吸附剂分散固相萃取-气相色谱-三重四级杆串联质谱法测定鸡肉和猪肉中的五氯酚[J]. 实用预防医学, 2022, 29(11): 1351-1353.
XU Ling-zhen, HU Ming-you, YAO Jian-hua. Determination of pentachlorophenol in chicken and pork by QuEChERS-mixed adsorbent dispersive solid phase extraction with gas chromatography-triple quadrupole mass spectrometry. , 2022, 29(11): 1351-1353.
2022, Vol. 29 
