Abstract：Objective To analyze the relationship between body mass index (BMI) and fatty liver, to clarify the BMI cut-off value of fatty liver so as to intervene the high-risk groups in time. Methods We collected the physical examination data about 24,019 adults undergoing medical check-ups in the Health Management Center of Hunan Provincial People's Hospital from January 2020 to August 2021. According to the current overweight and obesity standards in China, they were divided into the underweight group, the normal group, the overweight group and the obese group. Binary logistic regression analysis was used to evaluate the risk of fatty liver in the four groups. The receiver operator characteristic (ROC) curve was used to determine the BMI cut-off value of fatty liver. Results The prevalence rate of fatty liver among the subjects undergoing physical examination in Changsha was 35.64%. After correction for confounding factors in binary logistic regression analysis, the results showed that the risk of fatty liver in the overweight and obese groups was 2.946 times and 9.168 times higher than that of the normal group (both P<0.05), respectively, indicating that the elevated BMI was an independently risk factor for fatty liver. The risk of fatty liver disease in the overweight and obese groups varied by different triglyceride and high density liptein cholesterol levels (Pinteraction<0.05). The ROC curve revealed that the cut-off value of BMI for fatty liver in males was 24.60, and the area under curve (AUC) 0.814. The cut-off value of BMI for fatty liver in females was 23.20, and the AUC 0.848. Conclusion The elevated BMI is an independent risk factor for fatty liver, which has a certain predictive value for fatty liver. When male BMI is more than 24.60 and female BMI more than 23.20, special attention should be paid to weight management so as to reduce the occurrence of fatty liver.
张超, 李慧, 邵正健. 长沙体检人群身体质量指数与脂肪肝关系的探讨[J]. 实用预防医学, 2022, 29(11): 1346-1350.
ZHANG Chao, LI Hui, SHAO Zheng-jian. Relationship between body mass index and fatty liver among physical examination population in Changsha. , 2022, 29(11): 1346-1350.
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