Abstract：Objective To explore high-risk factors of anemia among preschoolers so as to provide a reference basis for anemia prevention and control among children. Methods A 1∶1 matched case-control study was conducted. Preschoolers diagnosed with anemia in the blood routine test in Pingshan District of Shenzhen City from July 2018 to July 2019 were enrolled into the case group, and healthy preschoolers were selected as the control group according to class, gender and age matching. The related information was collected. Univariable and multivariable conditional logistic regression analyses were used to explore high-riskfactors of anemia in the preschoolers. Results The information about 301 cases and 301 controls was collected, and univariable analysis of 26 major factors was performed. The results displayed that preschoolers’ household register, mothers with anemia before or during pregnancy orduring breastfeedingperiod, mothers smoked actively or passively, gestationalage at delivery, G6PD deficiency and carrying thalassemia gene were statistically correlated with children’s anemia (P<0.05). The results of multivariable analysis revealed that children with mothers having anemia during pregnancy (OR=5.13, 95%CI:3.08-8.53), children carrying thalassemia gene (OR=16.80, 95%CI:5.03-56.18) and children with cold and cough in the past two weeks (OR=1.66, 95%CI:1.06-2.58) had a higher risk of anemia, but the risk of anemia was lower in children with older gestational age at delivery than in ones with younger gestational age at delivery (OR=0.57, 95%CI:0.39-0.85). Conclusion Mothers with anemia during pregnancy, carrying with thalassemia gene, suffering from cold and cough in the past two weeks, and gestational age at delivery are the main factors influencing anemia in children, and special attention should be paid tothese factorsin anemia prevention and control among children.
牟劲松, 周海山, 冯战桂, 黄诗雅, 汪育东, 张超宇. 深圳市坪山区学龄前儿童贫血危险因素的1∶1配比病例对照研究[J]. 实用预防医学, 2022, 29(9): 1076-1079.
MOU Jin-song, ZHOU Hai-shan, FENG Zhan-gui, HUANG Shi-ya, WANG Yu-dong, ZHANG Chao-yu. 1:1 matched case-control study on risk factors for anemia among preschool children in Pingshan District of Shenzhen City. , 2022, 29(9): 1076-1079.
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