Abstract：Objective To understand the etiological and epidemiological features of fever outbreaks in Zhejiang Province, and to provide reference for epidemic control. Methods We collected the information about outbreaks with fever cases reported in Zhejiang Province from 2013 to 2019, analyzed their etiological characteristics, and subgrouped the cases according to types of diseases. Characters of the attack rate, duration, and time, space and population distribution were analyzed according to different diseases. Etiological distribution and epidemiological characteristics of fever outbreaks with rash, throat pain, and cough were described. Results A total of 614 outbreaks with fever cases and 23 types of diseases were detected, and pathogens involved were as follows: norovirus (167 outbreaks), influenza virus(147 outbreaks), varicella-zoster virus(129 outbreaks), pathogens causing hand-foot-mouth disease(59 outbreaks), dengue virus(43 outbreaks), mumps virus(10 outbreaks), adenovirus(8 outbreaks), Chikungunya virus(8 outbreaks), human H7N9 avian influenza virus(8 outbreaks), Salmonella(7 outbreaks), new Bunia virus(5 outbreaks), diarrheagenic Escherichia coli(3 outbreaks), Brucella(3 outbreaks), Zika virus(3 outbreaks), rabies virus(2 outbreaks), Campylobacter jejuni(2 outbreaks), Japanese encephalitis virus(2 outbreaks), rhinovirus(1 outbreak), Chlamydia psittaci(1 outbreak), Zharu virus(1 outbreak), Vibrio parahaemolyticus(1 outbreak), and Neisseria meningitidis(1 outbreak). The median attack rates of norovirus, influenza, and chicken pox outbreaks were 3.52%, 6.82% and 2.16%, respectively, with the outbreak durations being 2.90 days, 19.17 days, and 36.00 days, respectively. There were two peaks, namely March-May and September-December, in the outbreaks, distributing all of the 11 cities in Zhejiang Province. The outbreak durations of varicella, mumps and brucellosis were more than one month. Outbreaks with the attack rate more than 30% were Japanese encephalitis, Zika virus disease, rabies, Chikungunya fever and brucellosis. There were 195 (31.76%) fever outbreaks with rash (involving 8 types of diseases), 200 (32.57%) fever outbreaks with throat pain (involving 11 types of diseases) and 211 (34.36%) fever outbreaks with cough (involving 13 types of diseases). Conclusion The fever outbreaks in Zhejiang Province during 2013-2019 were caused by various pathogens, and the epidemiological characters were complex. It is of great reference value for judging and timely handling the epidemic to understand etiology of the fever outbreaks.
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2022, Vol. 29 
