Abstract：Objective To systematically evaluate the association betweenintake of dietary sugar-sweetened beverages (SSBs) and risk of hyperuricemia (HUA) based on a meta-analysis. Methods Databases of PubMed, CNKI, Wanfang Data, and VIP were systematically retrieved for choosing published observational studies on SSBs intake and risk of HUA as of December 31, 2021. The articles were screened strictly according to inclusion and exclusion criteria, and valid data were extracted. Stata v.16.0 was used to perform heterogeneity test, subgroup analysis, meta-regression analysis, sensitivity analysis, publication bias assessment and dose-response analysis. Results A total of 10 articles, including 1 case-control study and 9 cross-sectional studies, were enrolled in this study. 66,559 participants were involved, including 12,108 cases of HUA. The analysis results showed that dietary SSBs intake was a risk factor for occurrence of HUA (OR=1.37, 95%CI:1.25-1.49), and the results of dose-response analysisrevealed that there was a non-linear positive correlation between SSBs intake and risk of HUA. Conclusion There is a correlation between dietary SSBs intake and HUA, and high SSBs intake can increaserisk of HUA onset.
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2022, Vol. 29 
