Epidemiological characteristics and drug resistance in children with respiratorytract infection caused by Haemophilus influenzae in Huidong area, 2013-2015
LIN Hua-jie, ZHOU Shi-juan, ZHOU Wen-juan
The People’s Hospital of Huidong County, Huidong, Guangdong 516300, China
Abstract：Objective To investigate the epidemiological characteristics and drug resistance of children with respiratory tract infection caused by Haemophilus influenzae in Huidong area so as to early prevent and control the infection. Methods We analyzed the data about 1,112 children with respiratory tract infections and hospitalized in the People’s Hospital of Huidong County from January 1, 2013 to December 30, 2015. The epidemiological characteristics of 105 cases of Haemophilus influenzae infection were summarized, and the drug resistance was analyzed. Results There were 105 cases of Haemophilus influenzae infection in 1,112 children with respiratory tract infections, accounting for 9.44%.Most of the105 cases of Haemophilus influenzae infection were children aged 2-4 years, accounting for 58.10%. There were two incidence peaks in winter and spring, accounting for 80.95% of the total cases. There were 31 cases with beta-lactamase-positive strain of Haemophilus influenzae, and the drug resistant rates to ceftriaxone, cefuroxime sodium, azithromycin and cefoperazone sulbactam were lower, but the rates to levofloxacin, ciprofloxacin, ampicillin and penicillin were all more than 50%. Biological distribution of Haemophilus influenzae showed biotypes Ⅱ and Ⅲ were the most common, accounting for 57.14% (60/105). Conclusions Most of the cases with respiratory tract infection caused by Haemophilus influenzaein Huidong area in 2013-2015 are children aged 2-3 years, and occur in winter and spring. Haemophilus influenzae biotypes II and Ⅲ are prevailing, and Haemophilus influenzae strains are sensitive to azithromycin and second and three generation cephalosporins.
林华杰, 周世娟, 周文娟. 2013-2015年惠东地区儿童呼吸道流感嗜血杆菌感染流行病学特征及耐药性分析[J]. 实用预防医学, 2017, 24(7): 831-832.
LIN Hua-jie, ZHOU Shi-juan, ZHOU Wen-juan. Epidemiological characteristics and drug resistance in children with respiratorytract infection caused by Haemophilus influenzae in Huidong area, 2013-2015. , 2017, 24(7): 831-832.
2017, Vol. 24 
