Abstract:Objective To understand the epidemiological features of foodborne Salmonella infection in Hunan Province so as to provide a scientific basis for its prevention and control. Methods Descriptive epidemiology method was used to statistically analyze the epidemiological information and laboratory test results of Salmonella infection cases from 10 foodborne disease surveillance sentinel hospitals in Hunan Province. Results A total of 7,506 foodborne disease cases and their biological specimens were collected from 2015 to 2019. The positive detection rate of Salmonella was 9.75%, and Salmonella typhimurium was the dominant serotype (accounting for 68.17%). In terms of the place of food ingestion, 86.61% of the cases occurred at home. The positive detection rate of Salmonella was higher in patients aged below 18 years (accounting for 58.41%). With the increase of age, the positive detection rate of Salmonella showed a downward trend (χ2=126.700, P<0.001). The positive detection rates of Salmonella in fever and dehydration cases were higher than those in non-fever (χ2=309.088, P<0.001) and non-dehydration cases (χ2=28.291, P<0.001). The positive detection rates of cases with intake of fruits and their products (χ2=19.798, P<0.001), infant foods (χ2=14.344, P=0.038), mixed foods (χ2=5.125, P<0.001), vegetables and their products (χ2=4.316, P<0.001), beans and soy products (χ2=11.146, P=0.001) were higher than those of uneaten cases. The positive detection rate of Salmonella was different in different seasons, and the positive detection rate was higher in the second and third quarters than in the first and fourth quarters (χ2=88.926, P<0.001). Conclusion Salmonella infection in Hunan Province mainly occurred at home. The exposed foods of the confirmed cases of Salmonella infection were mainly milk and dairy products, grain and their products, and fruits and their products. The results suggest that popular science propaganda about family food safety knowledge should be strengthened and the awareness of disease prevention should be improved.