Abstract：Objective To analyze the mortality and trends in hepatic cancer in Guangzhou City from 2010 to 2019, and to provide data support for scientific prevention and control of reducing liver cancer mortality. Methods The population data were provided by Guangzhou Public Security Bureau. The data of liver cancer deaths were collected through Population Death Information Registration and Management System from China Disease Prevention and Control Information System. The mortality rate, age-specific mortality rate, age-standardized incidence rate by world standard population (ASIRW) and annual percentage change (APC) were calculated. The Join Point Regression Program was applied to analyzing the changing trends of liver cancer mortality. Results The annual average mortality rate of liver cancer in Guangzhou City from 2010 to 2019 was 24.40/100,000. The mortality rate was higher in males (38.37/100,000) than in females (10.25/100,000), and the median age of deaths in males was 11 years earlier than that in females. 49.69% of male deaths due to liver cancer occurred in the age group of 45-64 years, and 68.95% of female deaths occurred in the age group of above 65 years. The overall, male and female mortality rates of liver cancer in recent 10 years showed decreasing trends and statistically significant differences, with the APC being -2.06%, -1.82% and -2.49%, respectively. The mortality of liver cancer in the age groups of 15-44, 45-64 and above 65 years presented decreasing trends, with the APC being -3.78%, -2.01% and -1.17%, respectively. Conclusion The mortality rates of liver cancer in Guangzhou City in recent 10 years show decreasing trends. Male and the elderly are the key groups for prevention and control. We should attach importance to liver cancer screening, further improve the health literacy of residents, and strengthen self-management ability so as to reduce the risk of death.
2021, Vol. 28 
