Surveillance of influenza in children at sentinel hospitals in Foshan City, 2012-2019
ZOU Lin1, XIE Dong-de1, WU Ming-xin2, LI Yan2
1. The Second People’s Hospital of Foshan City, Foshan, Guangdong 528000, China; 2. School of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou, Hainan 571199, China
Abstract:Objective To analyze the epidemic characteristics of influenza viruses among children in Foshan City so as to provide a scientific basis for prevention and control of influenza in children. Methods We collected influenza-like cases reported by influenza surveillance sentinel hospitals in Foshan City from 2012 to 2019. Pharyngeal swab specimens of the influenza-like cases were collected, and real-time fluorescent RT-PCR was used to detect influenza viruses. The monitoring results were statistically analyzed. Results A total of 4,441cases of children with influenza-like illnesswere detectedfrom 2012 to 2019, and 636 cases werepositive for influenza virus nucleic acid, with a positive rate of 14.32%. Among the positive specimens, influenza virus A accounted for 63.68% and influenza virus B 36.32%. The months with high incidence of influenza in children in Foshan City were found from December to March of the following year. The four seasons were all dominated by influenza virus A. The positive rate of new influenza A (H1N1) virus in spring was higher, while the positive rates of seasonal H3N2 influenza virus in summer, autumn and winter were higher. The positive rates of influenza B-Yamagata lineage virus in spring, autumn and winter were higher, while the positive rate of influenza B-Victoria lineage virus in summer was higher. Subsequent analysis by age group showed that theinfluenza-like cases were mainly distributed in children aged 0-5 years, but the positive rates of influenza viruses were not high. The influenza-like cases were seldom distributed in children aged 6-14 years, but the positive rate of influenza B-Victoria lineage virus was higher. No statistically significant differences were found in the positive rates of influenza virusesas well as in the proportions of different types and subtypes of influenza viruses between male and female children. Conclusions Influenza in children in Foshan City was mainly caused by influenza virus A, and low levels of influenza virus B were detected. Four types of influenza viruses, new influenza A (H1N1) virus, seasonal H3N2 influenza virus, B-Victoria lineage virus and B-Yamagata lineage virus alternated or were co-prevalent among children in Foshan City. Influenza vaccination should be strengthened among the local children.
邹林, 谢东德, 吴明新, 李岩. 佛山市2012—2019哨点医院儿童流感监测分析[J]. 实用预防医学, 2021, 28(4): 450-453.
ZOU Lin, XIE Dong-de, WU Ming-xin, LI Yan. Surveillance of influenza in children at sentinel hospitals in Foshan City, 2012-2019. , 2021, 28(4): 450-453.
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