1. Changning District Center for Disease Control and Prevention, Shanghai 200051, China; 2. School of Public Health, Fudan University, Shanghai 200032, China
Abstract：Objective To analyze the epidemiological characteristics of a family cluster of COVID-19 in Changning District, Shanghai, and to provide a scientific basis for prevention and control of cluster epidemic of COVID-19. Methods Field epidemiological methods were used to survey the cases and close contacts in a family cluster of COVID-19 in Changning District, Shanghai in 2020. Real-time fluorescence quantitative RT-PCRwas applied to detecting 2019-nCoV nucleic acid in the collected respiratory tract samples. Results Case A was the source of infection in this family cluster epidemic. There were 5 second-generation cases infected in the whole incubation period. Routes of transmission showed thatcases B,C,D and E were transmitted by case A through droplets and close contacts, and case F was transmitted by case A through droplets alone. Besides cough, fatigue and other respiratory symptoms, there were also gastrointestinal symptoms in case F.An asymptomatic COVID-19 carrierwas involved in this family cluster. Conclusions COVID-19 spreads easily in family. We should strengthen the tracking and management of close contacts of COVID-19 cases, and identify the second-generation cases as early as possible.
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