Abstract：Exosomes are nanoscale bilayer vesicles which can be secreted by many kinds of cells and exist in different body fluids. Exosomes can carry DNA, RNA, protein, lipid and other substances to receptor cells for information exchange between cells. In addition, exosomes have a variety of functions, which can participate in antigen presentation, immune activation, immunosuppression and other immune regulatory processes. In recent years, more and more studies have pointed out that exosomes play important roles in the pathogenesis of some pulmonary inflammatory diseases, such as chronic obstructive pulmonary disease (COPD) and asthma; moreover, they are also correlated with the diagnosis and staging of some pulmonary inflammatory diseases, such as COPD. Therefore, exosomes are expected to be a new diagnostic marker and target of biotherapy for these diseases. This article will introduce the research progress on exosomes in some inflammatory lung diseases.
孙梦婷, 李慧芹, 谭滇湘, 张朝晖. 外泌体在肺部炎症性疾病中的研究进展[J]. 实用预防医学, 2021, 28(1): 124-129.
SUN Meng-ting, LI Hui-qin, TAN Dian-xiang, ZHANG Zhao-hui. Research progress on exosomes in pulmonary inflammatory diseases. , 2021, 28(1): 124-129.
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