[1] World Health Organization. Media center: hepatitis C key facts[EB/OL]. (2018-07-18)[2019-01-11]. http://www.who.int/zh/news-room/fact-sheets/detail/hepatitis-c. [2] World Health Organization. Global hepatitis report, 2017[EB/OL]. (2017-04-01)[2019-01-11]. http://www.who.int/hepatitis/publications/global-hepatitis-report2017/en/. [3] World Health Organization. Media center: HIV/AIDS key facts[EB/OL]. (2018-07-19)[2018-08-01]. http://www.who.int/zh/news-room/fact-sheets/detail/hiv-aids. [4] Grint D, Peters L, Reekie J, et al. Stability of hepatitis C virus (HCV) RNA levels among interferon-naive HIV/HCV-coinfected individuals treated with combination antiretroviral therapy[J]. HIV Med,2013, 14(6):370-378. [5] Thornton AC, Jose S, Bhagani S, et al. Hepatitis B, hepatitis C, and mortality among HIV-positive individuals[J]. AIDS, 2017, 31(18):2525-2532. [6] Puoti M, Moioli MC, Travi G, et al. The burden of liver disease in human immunodeficiency virus-infected patients[J]. Semin Liver Dis,2012, 32(2):103-113. [7] Schlabe S, Rockstroh JK. Advances in the treatment of HIV/HCV coinfection in adults[J]. Expert Opin Pharmacother,2018, 19(1):49-64. [8] Terrault NA, Dodge JL, Murphy EL, et al. Sexual transmission of hepatitis C virus among monogamous heterosexual couples: the HCV partners study[J]. Hepatology, 2013,57(3):881-889. [9] Dienstag JL. Sexual and perinatal transmission of hepatitis C[J]. Hepatology, 1997, 26(3 Suppl 1):66S-70S. [10] 王丽艳,秦倩倩,丁正伟,等.中国艾滋病全国疫情数据分析[J].中国艾滋病性病,2017,23(4):330-333. [11] Ghazaryan L, Smith L, Parker M, et al. Hepatitis C seroprevalence among HIV-infected childbearing women in New York state in 2006[J]. Matern Child Health J, 2016, 20(3):550-555. [12] 苏迎盈,汪宁.丙型肝炎病毒感染主要危险因素的meta分析[J].中华流行病学杂志,2011,32(9):940-945. [13] Degenhardt L, Peacock A, Colledge S, et al. Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review[J]. Lancet Glob Health,2017, 5(12):e1192-e1207. [14] Taylor LE, Holubar M, Wu K, et al. Incident hepatitis C virus infection among US HIV-infected men enrolled in clinical trials[J].Clin Infect Dis,2011, 52(6):812-818. [15] Cacoub P, Dabis F, Costagliola D, et al.Burden of HIV and hepatitis C co-infection: the changing epidemiology of hepatitis C in HIV-infected patients in France[J].Liver Int, 2015, 35(1):65-70. [16] Rao VB, Johari N, du Cros P, et al. Hepatitis C seroprevalence and HIV co-infection in sub-Saharan Africa: a systematic review and meta-analysis[J]. Lancet Infect Dis,2015, 15(7):819-24. [17] Matthews PC, Geretti AM, Goulder PJR, et al. Epidemiology and impact of HIV coinfection with hepatitis B and hepatitis C viruses in Sub-Saharan Africa[J]. J Clin Virol,2014, 61(1):20-33. [18] 冯丹. 中国HIV/AIDS患者HBV/HCV合并感染现状及其影响因素的系统综述与meta分析[D].太原:山西医科大学,2018. [19] Beyrer C, Baral SD, Van GF, et al. Global epidemiology of HIV infection in men who have sex with men[J]. Lancet, 2012, 380(9839):367-377. [20] Chan DP, Sun HY, Wong HT, et al. Sexually acquired hepatitis C virus infection: a review[J].Int J Infect Dis,2016, 49:47-58. [21] Jordan AE, Perlman DC, Neurer J, et al. Prevalence of hepatitis C virus infection among HIV+ men who have sex with men: a systematic review and meta-analysis[J].Int J STD AIDS,2017,28(2):145-159. [22] Urbanus AT, Van De Laar TJ, Geskus R, et al. Trends in hepatitis C virus infections among MSM attending a sexually transmitted infection clinic; 1995-2010[J]. AIDS, 2014, 28(5):781-790. [23] Dougan S, Balogun MA, Elford J, et al. Can current national surveillance systems in England and Wales monitor sexual transmission of hepatitis C among HIV-infected men who have sex with men?[J]. BMC Public Health, 2007, 7(1):7. [24] Price H, Gilson R, Mercey D, et al. Hepatitis C in men who have sex with men in London–a community survey[J]. HIV Med,2013, 14(9):578-580. [25] Raymond HF, Hughes A, O'Keefe K, et al. Hepatitis C prevalence among HIV-positive MSM in San Francisco: 2004 and 2008[J]. Sex Transm Dis,2011, 38(3):219-220. [26] Centers for Disease Control and Prevention (CDC).Sexual transmission of hepatitis C virus among HIV-infected men who have sex with men -- New York City, 2005-2010[J]. MMWR Morb Mortal Wkly Rep,2011, 60(28):945-950. [27] Ohto H, Terazawa S, Sasaki N, et al. Transmission of hepatitis C virus from mothers to infants. The Vertical Transmission of Hepatitis C Virus Collaborative Study Group[J]. N Engl J Med, 1994, 330(11):744-750. [28] Cottrell EB, Chou R, Wasson N, et al. Reducing risk for mother-to-infant transmission of hepatitis C virus: a systematic review for the U.S. Preventive Services Task Force[J]. Ann Intern Med,2013,158(2):109-113. [29] Snijdewind IJ, Smit C, Schutten M, et al. Low mother-to-child-transmission rate of hepatitis C virus in cART treated HIV-1 infected mothers[J]. J Clin Virol,2015, 68:11-15. [30] Polis CB, Shah SN, Johnson KE, et al. Impact of maternal HIV coinfection on the vertical transmission of hepatitis C virus: a meta-analysis[J]. Clin Infect Dis, 2007, 44(8):1123-1131. [31] Engupta S, Powell E, Kong L, et al. Effects of HCV on basal and tat-induced HIV LTR activation[J]. PLoS One, 2013, 8(6):e64956. [32] Kang L, Luo Z, Li Y, et al. Association of Vpu with hepatitis C virus NS3/4A stimulates transcription of type 1 human immunodeficiency virus[J]. Virus Res,2012, 163(1):74-81. [33] Khan KA, Abbas W, Varin A, et al. HIV-1 Nef interacts with HCV core, recruits TRAF2, TRAF5 and TRAF6, and stimulates HIV-1 replication in macrophages[J]. J Innate Immun,2013,5(6):639-656. [34] Greub G, Ledergerber B, Battegay M, et al. Clinical progression, survival, and immune recovery during antiretroviral therapy in patients with HIV-1 and hepatitis C virus coinfection: the Swiss HIV Cohort Study[J]. Lancet, 2000, 356(9244):1800-1805. [35] 李媛媛, 张程达, 郗园林,等. HIV/HCV合并感染者的生物学特征与生存分析[J]. 郑州大学学报(医学版), 2015, 50(3):371-374. [36] Grint D, Peters L, Rockstroh JK, et al. Liver-related death among HIV/hepatitis C virus-co-infected individuals[J].AIDS, 2015, 29(10):1205-1215. [37] Eyster ME , Fried MW , Di Bisceglie AM , et al. Increasing hepatitis C virus RNA levels in hemophiliacs: relationship to human immunodeficiency virus infection and liver disease. Multicenter Hemophilia Cohort Study[J]. Blood, 1994, 84(4):1020. [38] Lin W, Weinberg EM, Tai AW, et al. HIV increase HCV replication in a TGF-beta1-dependent manner[J]. Gastroenterology, 2008, 134(3):803-811. [39] Park IW, Fan Y, Luo X, et al. HIV-1 Nef is transferred from expressing T cells to hepatocytic cells through conduits and enhances HCV replication[J]. PLoS One, 2014, 9(6):e99545. [40] Mastroianni CM, Lichtner M, Mascia C, et al. Molecular mechanisms of liver fibrosis in HIV/HCV coinfection[J]. Int J Mol Sci,2014, 15(6):9184-9208. [41] Qu J, Yang Z, Zhang Q, et al. Human immunodeficiency virus-1 Rev protein activates hepatitis C virus gene expression by directly targeting the HCV 5'-untranslated region[J]. FEBS Lett,2011, 585(24):4002-4009. [42] Romero A, Lagging M, Westin J, et al. Interferon (IFN)-gamma-inducible protein-10: association with histological results, viral kinetics, and outcome during treatment with pegylated IFN-alpha 2a and ribavirin for chronic hepatitis C virus infection[J]. J Infect Dis,2006, 194(7):895-903. [43] Nobile C, Rudnicka D, Hasan M, et al. HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes[J]. J Virol,2010, 84(5):2282-2293. [44] Rockstroh JK, Hardy WD . Current treatment options for hepatitis C patients co-infected with HIV[J]. Expert Rev Gastroenterol Hepatol, 2016, 10(6):689-695. [45] 吴霞, 罗志, 杨丽华,等. 云南省某艾滋病抗病毒治疗门诊HIV/HCV共感染者 肝纤维化及丙肝治疗服务情况分析[J]. 实用预防医学, 2018, 25(8):968-970. [46] Lo Re 3rd V, Kallan MJ, Tate JP, et al. Hepatic decompensation in antiretroviral-treated patients co-infected with HIV and hepatitis C virus compared with hepatitis C virus-monoinfected patients: a cohort study[J]. Ann Intern Med,2014, 160(6):369-379. [47] World Health Organization. Guidelines for the care and treatment of persons diagnosed with chronic hepatitis C virus infection, 2018[EB/OL]. (2018-08-01)[2019-01-11]. https://www.who.int/hepatitis/publications/hepatitis-c-guidelines-2018/en/. [48] 中华医学会肝病学分会,中华医学会感染病学分会. 丙型肝炎防治指南(2019年版)[J]. 临床肝胆病杂志, 2019,35(12):2670-2686.