Abstract：New infectious diseases are constantly emerging and prevailing in recent years, and arbovirus diseases threatened to human health are gradually increased. The first strain of Nam Dinh virus in the world is a new type of virus isolated in cerebrospinal fluid of a patient with encephalitis in Vietnam; moreover, it is also found in Culex pipiens quinquefasciatus and other Culex mosquitoes. A Japanese scientist, Nga names it Nam Dinh virus in 2012 because the location of separation of the virus is in Nam Dinh Province, Vietnam. The author discovers and isolates Nam Dinh virus in Culex pipiens quinquefasciatus for the first time in China in 2013. This papar reviews the characteristics of Nam Dinh virus and its research situation.
王德全,刘渠,梁克峰,周健明. 新型虫媒病毒—南定病毒的研究进展[J]. 实用预防医学, 2017, 24(5): 638-642.
WANG De-quan, LIU Qu, LIANG Ke-feng, ZHOU Jian-ming. Research progress of new arbovirus virus - Nam Dinh virus. , 2017, 24(5): 638-642.
[1] Stramer SL. Current perspectives in transfusion-transmitted infectious diseases: emerging and re-emerging infections[J]. ISBT Sci Ser, 2014,9(1):30-36. [2] Grace D, Jeffrey G, Lapar MLA,et al. Zoonotic emerging infectious disease in selected countries in Southeast Asia: insights from ecohealth[J]. Ecohealth, 2011,8(1):55-62. [3] Jones KE, Patel NG, Levy MA, et al.Global trends in emerging infectious diseases[J]. Nature, 2008,451(7181):990. [4] Wang L, Valderramos SG, Wu A, et al. From mosquitos to humans: genetic evolution of Zika virus[J]. Cell Host Microbe,2016, 14(1):1931-3128. [5] 张海林,梁国栋. 中国虫媒病毒和虫媒病毒病[J]. 中国媒介生物学及控制杂志, 2012,28(5):377-380. [6] Zirkel F, Kurth A, Quan PL, et al. An insect nidovirus emerging from a primary tropical rainforest[J]. MBio, 2011,2(1):e11-e77. [7] Nga PT, Parquet MC, Lauber C, et al. Discovery of the first insect nidovirus, a missing evolutionary link in the emergence of the largest RNA virus genomes[J]. PLoS Pathog, 2011,7(9):e1002215. [8] Zirkel F, Roth H, Kurth A, et al. Identification and characterization of genetically divergent members of the newly established family Mesoniviridae[J]. Virol, 2013,87(11):6346. [9] Gorbalenya AE,Enjuanes L,Ziebuhr J,et al. Nidovirales:evolving the largest RNA virus genome [J] . Virus Res,2006,117(1):17-37. [10] Lauber C, Ziebuhr J, Junglen S, et al. Mesoniviridae: a proposed new family in the order Nidovirales formed by a single species of mosquito-borne viruses[J]. Arch Virol, 2012,157(8):1623-1628 [11] Liu Q, Lin L, Zhou JM, et al. Identification of Nam Dinh virus in China[J]. Bing Du Xue Bao, 2013, 29(1):1-6. [12] Gorbalenya AE, Enjuanes L, Ziebuhr J, et al. Nidovirales: evolving the largest RNA virus genome[J]. Virus Res, 2006,117(1):17-37. [13] 周健明. 深圳市龙岗区部分蚊传虫媒病毒的分子流行病学研究[D].广州:广东药学院,2013. [14] Lapied B, Pennetier C, Apaire-Marchais V, et al. Innovative applications for insect viruses: towards insecticide sensitization[J]. Trends Biotechnol, 2009, 27(4):190-198. [15] Vasilakis N, Tesh RB. Insect-specific viruses and their potential impact on arbovirus transmission[J].Curr Opin Virol, 2015,15(1):69-74. [16] Teurlai M, Huy R, Cazelles B, et al. Can human movements explain heterogeneous propagation of dengue fever in Cambodia?[J]. PLoS Negl Trop Dis, 2012, 6(12): e1957. [17] Thuy NT, Huy TQ, Nga PT, et al. A new nidovirus (NamDinh virus NDiV): its ultrastructural characterization in the C6/36 mosquito cell line[J]. Virology, 2013,444(1-2):337-342. [18] Bolling BG, Weaver SC, Tesh RB. Insect-specific virus discovery: significance for the arbovirus community[J]. Viruses,2015 ,7(9):4911. [19] Becnel JJ, White SE. Mosquito pathogenic viruses-the last 20 years[J]. Am Mosq Control Assoc, 2007,23(1):36-49. [20] Kean J, Rainey SM, McFarlane M,et al. Fighting arbovirus transmission: natural and engineered control of vector competence in Aedes mosquitoes[J].Insects, 2015,6(1):236-278. [21] Becnel JJ.Transmission of viruses to mosquito larvae mediated by divalent cations[J].Invertebr Pathol, 2006,92(3):141-145. [22] 张荣. 基于反向遗传平台的套式病毒蛋白结构与功能研究[D].北京:中国农业科学院,2013. [23] 梁克峰. NDiV致病性初步研究及实时荧光PCR检测方法的建立 [D].广州:广东药学院,2016. [24] 梁克峰,刘渠,王德全,等.实时荧光PCR检测Nam Dinh病毒方法的建立及初步应用[J].中国媒介生物学控制杂志,2015,26(5):443-450. [25] 王德全,刘渠,周建明,等.南定病毒标准血清制备及间接ELISA检测方法的建立[J].实用预防医学,2016,23(9):1144-1146,封三.
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