Abstract：There have been multiple outbreaksall over the worldsince the occurrence of coronavirus disease 2019 (COVID-19), and the epidemic has rapidly spread. At present, the domestic epidemic situation is basically controlled, but the overseas epidemic is still relatively grim. The primary and secondary school students are about to resume school one after another; and hence, it is particularly important to prevent and control the epidemic situation in children. This article combines the currentepidemic prevention and control situation with scientific research advances and uses the method of literature review to clarify the clinical and epidemiological characteristics of children with COVID-19 and current status of prevention and control measures so as to improve readers' awareness of COVID-19, remind parents, schools and all the relevant societal organizations to work together and do a good job in children's health management, and win the battle of epidemic prevention and control in a scientific,standardized, orderly and efficient manner.
[1] 世界卫生组织. 2019冠状病毒病(COVID-19)疫情[EB/OL].(2020-04-04)[2020-04-04].https://experience.arcgis.com/experience/62c28590b5ae41ef920e4d5a4128504a. [2] 国家卫生健康委员会. 疫情通报[EB/OL].(2020-04-04)[2020-04-04].http://www.nhc.gov.cn/xcs/yqfkdt/202003/8721a8bc007b4 48db32489ea74b321fc.shtml. [3] 刘洁, 罗万军, 邓志宏, 等. 91例儿童新型冠状病毒肺炎确诊病例临床及流行病学特征[J].中华医院感染学杂志,(2020-03-27)[2020-03-29].http://kns.cnki.net/kcms/detail/11.3456.R.20200326.1721.007.html. [4] 张孝国, 马艳, 肖嘉安, 等. 济南地区儿童新型冠状病毒感染的肺炎临床特征[J].山东大学学报(医学版),2020,58(3):62-64. [5] 王端, 鞠秀丽, 谢峰, 等. 中国北方六省(自治区)儿童2019新型冠状病毒感染31例临床分析[J].中华儿科杂志,2020,58(4):269-274. [6] 马耀玲, 夏胜英, 王敏, 等. 115例新型冠状病毒感染儿童的临床特点分析[J].中国当代儿科杂志,2020,22(4):290-293. [7] 张国勋, 张爱民, 黄丽, 等. 一对双胎女童同时感染新型冠状病毒[J].中国当代儿科杂志,2020,22(3):221-225. [8] 刘苗, 万曦, 涂晓燕, 等. 一起家庭聚集性儿童感染新型冠状病毒分析[J].武汉大学学报(医学版),2020,41(3):362-365. [9] 赵瑞红, 沈晓敏, 徐凯进, 等. 儿童感染2019新型冠状病毒1例[J].浙江医学,2020,42(4):305-306. [10] 陈 锋, 刘智胜, 张芙蓉, 等. 中国首例儿童危重型新型冠状病毒肺炎[J].中华儿科杂志,2020,58(3):179-183. [11] 李旭芳, 郑健斌, 徐翼, 等. 广东省儿科新型冠状病毒肺炎诊疗专家共识[J].广东医学,2020,41(3):217-221. [12] Zhu HP,Wang L,Fang CZ,et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia[J].Transl Pediatr,2020,9(1):51-60. [13] 张露, 江燕, 魏敏, 等. 湖北地区新型冠状病毒肺炎流行期间孕妇的妊娠结局分析[J].中华妇产科杂志,2020,55(3):166-171. [14] 张明强, 王小辉, 安宇林, 等. 2019新型冠状病毒肺炎早期临床特征分析[J].中华结核和呼吸杂志,2020,43(3):215-218. [15] 佘佳桐, 刘文君. 儿童新型冠状病毒肺炎的流行病学特征与防控措施[J].热带医学杂志,2020,20(2):153-155,172. [16] Xu Y, Li X, Zhu B, et al. Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding[J].Nat Med,2020,26(4):502-505. [17] 中国疾病预防控制中心新型冠状病毒肺炎应急响应机制流行病学组.新型冠状病毒肺炎流行病学特征分析[J].中华流行病学杂志,2020,41(2):145-151. [18] Holshue ML, DeBolt C, Lindquist S, et al. First case of 2019 novel coronavirus in the United States[J]. N Engl J Med,2020,82(10):929-936. [19] Ki M, NCoV T. Epidemiologic characteristics of early cases with 2019 novel coronavirus (2019-nCoV) disease in Republic of Korea[J/OL].Epidemiol Health,(2020-02-09)[2020-03-30].https://doi.org/10.4178/epih.e2020007. [20] 邵明鸣,赵宏明,陈文艳,等.洛匹那韦/利托那韦在新型冠状病毒肺炎特殊人群治疗中的合理使用及药学监护[J].中国医院药学杂志,2020,40(7):753-756. [21]李璐, 陈娜, 孔丽敏, 等. 新型冠状病毒感染特殊人群的抗病毒药物治疗方案[J].中国现代应用药学,2020,37(3):257-263. [22] Shen KL, Shang YX, Zhang GC, et al. Expert consensus on the rational application of interferon alpha in pediatrics[J].J Appl Clin Pediatr,2018,33(17):1301-1308. [23] Drinevskii VP, Osidak LV, Natsina VK, et al. Chemotherapeutics for treatment of influenza and other viralrespiratory tract infections in children[J].Antibiot Khimioter,1998,43(9):29-34. [24] 陈致雯, 卢焯明. 阿比多尔颗粒治疗儿童流行性感冒疗效观察[J].现代中西医结合杂志,2014,23(14):1528-1529. [25] Mulangu S, Dodd LE, Davey RJ, et al. A randomized,controlled trial of Ebola virus disease therapeutics [J].N Engl J Med,2019,381(24):2293-2303. [26] 国家卫生健康委员会,国家中医药管理局. 新型冠状病毒肺炎诊疗方案(试行第七版)[Z].2020-03-03. [27] 朱月玲, 杨斌斌, 吴芳. 中西医不同角度对儿童新型冠状病毒肺炎(COVID-19)的认识[J].中草药,2020,51(4):883-887. [28] 国家卫生健康委员会,国家中医药管理局. 新型冠状病毒肺炎诊疗方案(试行第四版)[Z].2020-01-27. [29] 蔡洁皓, 王相诗, 葛艳玲. 上海首例儿童新型冠状病毒感染[J].中华儿科杂志,2020,58(2):85-86. [30] Xu X, Chen P, Wang J, et al. Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission.[J].Sci China Life Sci,2020,3(3):457-460. [31] 庹虎, 刘芳, 王军陵, 等. 儿童新型冠状病毒感染的临床特征及家庭防控[J].武汉大学学报(医学版),2020,41(3):357-361. [32] Stockman LJ, Massoudi MS, Helfand R, et al. Severe acute respiratory syndrome in children[J]. Pediatr Infect Dis J,2007,26(1):68-74. [33] Habet F, Chehab M, Bafaqih H, et al. Middle East respiratory syndrome coronavirus in children[J]. Saudi Med J, 2015,36(4):484-486. [34] 国家卫生健康委员会. 中国—世界卫生组织新型冠状病毒肺炎联合专家考察组新闻发布会文字实录[EB/OL]. (2020-02-25)[2020-04-04].http://www.nhc.gov.cn/gjhzs/s3578/202002/1fa99f55972740f681d47cde0d1b2522.shtml. [35] Wang FS ,Zhang C. What to do next to control the 2019-nCOV epidemic[J].Lancet,2020,395(10222):391-393. [36] Chen C, Gao G, Xu Y, et al. MDSARS-CoV-2-positive sputum and feces after conversion of pharyngeal samples in patients with COVID-19[J/OL].Ann Intern Med, (2020-03-30)[2020-04-02].https://doi.org/10.7326/M20-0991. [37] 国家卫生健康委员会,国家中医药管理局.新型冠状病毒肺炎诊疗方案(试行第五版)[Z].2020-02-04. [38] Xu Y, Li X, Zhu B, et al. Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding[J].Nat Med,2020,26(4):502-505. [39] 中国网. 新冠病毒是否存在粪口传播？[EB/OL].(2020-03-18)[2020-04-04].http://health.china.com.cn/2020-03/18/content_41094781.htm. [40] Schaefer E,Harms C, Viner M, et al. Investigation of an experimental infection model of equine coronavirus in adult horses [J].Vet Intern Med,2018,32(6):2099-2104. [41] Jones RM, Brosseau LM. Aerosol transmission of infectious disease[J].Occup Environ Med,2015,57(5):501-508. [42] Chen H, Guo J, Wang C, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant woman: a retropeciive review of medical records[J].Lancet,2020,26(4):502-505. [43] 李芳, 包蕾, 王建辉, 等. 新型冠状病毒感染流行期间NICU的应急准备方案(第二版)[J].中国当代儿科杂志,2020,22(3):205-210. [44] Wei-jie Guan,Zheng-yi Ni,Yu Hu,et al. Clinical characteristics of 2019 novel coronavirus infection in china[J].New Engl J Med,2020,382(18):1708-1720. [45] 央广网. 儿童新型冠状病毒感染的肺炎诊疗指南今天发布[EB/OL].(2020-01-31)[2020-04-04].http://zj.cnr.cn/zjyw/20200131/t20200131_524955330.shtml. [46] 国家健康委员会.关于做好儿童和孕产妇新型冠状病毒感染的肺炎疫情防控工作的通知[DB/OL].(2020-02-02)[2020-04-04].http://www.nhc.gov.cn/fys/s7902/202002/de2d62a5711c41ef9b2c4 b6f4d1f2136.shtml. [47] 湖北省医学会儿科学分会. 武汉会儿科学分会. 湖北省儿科医疗质量控制中心. 湖北省儿童新型冠状病毒感染诊疗建议(试行第一版)[J].中国当代儿科杂志医学,2020,22(2):96-99. [48] 世界卫生组织.2019冠状病毒病(COVID-19)疫情[EB/OL].(2020-03-27) [2020-04-04].https://www.who.int/zh/emergencies/diseases/novel-coronavirus-2019. [49] 尹进, 宋江南, 高琼, 等. 精准防护——口罩的有效使用及处理[J].实用预防医学,2020,27(4):403-405. [50] 周静, 郎楠, 袁媛, 等. 新型冠状病毒肺炎疫情呼吸防护及对策建议[J].职业卫生与应急救援,2020,38(2):116-119,182. [51] 国家标准化管理委员会. 关于征求《儿童口罩技术规范》(征求意见稿)意见的通知[EB/OL].(2020-03-20)[2020-04-04].http://www.sac.gov.cn/gzfw/zqyj/202003/t20200320_346311.htm. [52] 国家标准化管理委员会. 广州市市场监管局帮扶企业制定《一次性儿童用防护口罩》企业标准[EB/OL].(2020-03-05)[2020-04-04]. http://www.sac.gov.cn/xw/bzhdt/202003/t20200305_344186.htm. [53] 中华人民共和国中央人民政府. 浙江率先发布首个儿童口罩团体标准[EB/OL].(2020-03-12)[2020-04-04].http://www.gov.cn/xinwen/2020-03/13/content_5491032.htm.
2020, Vol. 27 
