Abstract:Objective To conduct an epidemiological analysis of type 2 diabetes mellitus (T2DM) patients complicated by diabetic retinopathy (DR) in Qinhuangdao region. Methods Three communities selected in Qinhuangdao region by using a cluster sampling method served as the surveyed sites. 1,133 T2DM patients who met the inclusion criteria from June 2015 to December 2018 were selected as the research subjects, and screening examination of the subjects for retinopathy was performed. Single factor chi-square test and multi-factor non-conditional logistic regression analysis were conducted to identify the risk factors for DR. Results The incidence rate of DR in 1,133 patients with T2DM was 19.24% (218/1,133), with the incidence rates of non-proliferative and proliferative DR being 13.15% and 6.09%, respectively. Logistic regression analysis showed that 7 indexes, age (≤60 years old) (OR=2.824, 95%CI: 2.254-3.537), junior middle school education level or below (OR=1.169, 95%CI:1.106-1.235), place of residence-suburban county (OR=3.102, 95%CI:1.867-5.153), history of internal eye surgery (OR=5.124, 95%CI:2.637-9.959), course of diabetes mellitus (>10 years) (OR=2.782, 95%CI:2.468-3.135), hypertension (OR=2.726, 95%CI:1.453-5.115) and fasting blood glucose (> 6.11 mmol/L) (OR=3.146, 95%CI: 2.491-3.972) were independent risk factors for developing DR. Conclusions The prevalence rate of DR in 1,133 patients with T2DM in Qinhuangdao region was 18.65%. Age (≤60 years old), junior middle school education level or below, place of residence-suburban county, history of internal eye surgery, course of diabetes mellitus (>10 years), hypertension and fasting blood glucose (> 6.11 mmol/L) were independent risk factors for DR. The model is expected to be used to guide, predict, intervene and treat DR in patients with T2DM, and it can reduce the incidence of DR and improve the visual acuity of T2DM patients.
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