Abstract：Objective To analyze the clinical characteristics and factors affecting death among HIV/AIDS patients complicated with pulmonary tuberculosis in Zhengzhou region. Methods We retrospectively analyzed the clinical data regarding 114 HIV/AIDS patients complicated with pulmonary tuberculosis in Zhengzhou region from January 2016 to December 2018. All the patients were divided into the survival group and the death group according to the follow-up results. Their clinical infection characteristics were analyzed, and multivariate logistic regression analysis was used to identify the independent risk factors affecting patients’ death. Results The patients were infected with HIV firstly (71.05%). The main stage of HIV/AIDS infection was the AIDS stage (90.35%). The major imaging findings were active foci (79.82%). There were many patients with initial CD4+T cell count less than 50 cells/mm3 (48.25%). There existed statistically significant differences in the age at diagnosis of HIV infection, route of infection, initial CD4+T cell count and antiviral treatment between the survival group and the death group (all P<0.05). Multivariate logistic regression analysis showed that route of transmission by injection drug use, (OR=1.782, 95%CI:1.179-2.695), age at diagnosis of HIV infection more than 40 years(OR=1.820, 95%CI:1.225-2.705), having no antiviral therapy(OR=1.719, 95%CI:1.157-2.555)and initial CD4+T cell count less than 200 cells/mm3(OR=1.655, 95%CI:1.105-2.479)were all the independent risk factors for death due to co-infection with HIV/AIDS and pulmonary tuberculosis. Conclusions As for the patients co-infected with HIV/AIDS and pulmonary tuberculosis, we should pay close attention to the patients with route of transmission through injection drug use, above 40 years of age, without receiving antiviral therapy and with lower initial CD4+T cell count, actively give medical aid to them, improve their immune function and strengthen the propaganda about harm of drugs so as to reduce the co-infection rate and prolong their lives.
陈春勇, 刘征, 李喜英, 韩涛, 仇元营. 郑州地区114例艾滋病合并肺结核双重感染患者临床特征及死亡影响因素分析[J]. 实用预防医学, 2020, 27(4): 442-445.
CHEN Chun-yong, LIU Zheng, LI Xi-ying, HAN Tao, QIU Yuan-ying. Clinical characteristics and factors influencing death in 114 patients co-infected with HIV/AIDS and pulmonary tuberculosis in Zhengzhou region. , 2020, 27(4): 442-445.
2020, Vol. 27 
