1. Beihai Center for Disease Control and Prevention, Beihai, Guangxi 536000, China; 2. Chinese Field Epidemiology Training Program, Chinese Center for Disease Control and Prevention, Beijing 100050, China
Abstract：Objective To analyze the epidemiological features of hand, foot and mouth disease (HFMD) in Beihai city from 2008 to 2018, and to provide a scientific basis for HFMD prevention and control. Methods HFMD cases in Beihai city during 2008-2018 were collected from the Chinese Information System for Disease Control and Prevention. Descriptive epidemiological methods were used to analyze the incidence time, regional and population distribution characteristics of the cases; meanwhile, samples of some cases were tested in the laboratory. Results A total of 75,211 cases of HFMD were reported in Beihai city during 2008-2018, with an average annual incidence rate of 431.09/100,000. There were 185 (0.25%) severe cases and 14 deaths, and the case fatality rate was 18.61/100,000. A total of 2,846 HFMD samples were tested in the polymerase chain reaction laboratory of HFMD in Beihai city during 2008-2018, and 2,222 positive samples were detected (with the positive rate of 78.07%). Universal enteroviruses (37.18%) were the main virus types in mild cases, while EV71 (90.32%) was the main virus type in severe cases. The incidence peak mainly occurred during April-June, but there was a secondary incidence peak observed in September-November. The reported incidence rate was found to be the highest in Haicheng district, and most of the cases were scattered children aged 1-3 years. Conclusions The incidence rate of HFMD was found to be the highest among the notifiable infectious diseases in Beihai city from 2008 to 2018. The phenomenon about a 2- or 3-year epidemic cycle of HFMD will still exist for a long time. HFMD prevention and control should focus onearly intervention before the incidence peak period and strengthen target publicity and education in the key population aged below 5 years, especially in scattered children.
2020, Vol. 27 
