Risk factors of measles among children in Shufu county, Xinjiang
ZHOU Zi-yan1, XIE Huo-qiang2, LI Xiao-ning1, XUE Zhen-xiang1, ZHANG Zhou-bin1
1.Guangzhou Municipal Center for Disease Control and Prevention, Guangzhou, Guangdong 510440, China; 2.Conghua District Center for Disease Control and Prevention, Guangzhou, Guangdong 510925, China; 3.Shufu County Center for Disease Control and Prevention, Kashgar, Xinjiang 844100, China
Abstract：Objective To explore the factors influencing measles incidence in children in Shufu county, Xinjiang, and to provide evidence for formulating measles prevention and control strategies. Methods Using a 1:1 matched case-control study, 125 laboratory-confirmed measles cases aged 8 months to 14 years and 125 control cases in Shufu county, Xinjiang from 2016 to 2018 were selected as the surveyed subjects. A questionnaire was designed to retrospectively collect relevant data which might affect the incidence of measles in children, and conditional logistic regression was used to analyze the influencing factors. Results Multivariate logistic regression analysis showed that the hospital visiting history in the past one month was a risk factor for measles in children (OR=4.876, 95%CI:1.350-17.608), while indoor ventilation (OR=0.103, 95%CI:0.039-0.269), parents’ qualified awareness of measles (OR=0.187, 95%CI:0.071-0.493) and children’s measles component vaccination (OR=0.475, 95%CI:0.290-0.778) were protective factors for measles in children. Conclusions It is necessary to enhance the administration of nosocomial infections in hospitals in Shufu county and strengthen publicity and education of measles prevention and control so as to comprehensively improve the measles vaccination rate in children.
[1] Wallace G, Redd S, Rota J, et al. Measles - United States, January 1-August 24, 2013[J]. MMWR Morb Mortal Wkly Rep, 2013, 62(36):741-743. [2] World Health Organization. Progress in global control and regional elimination of measles, 2000-2011[J]. Wkly Epidemiol Rec,2013,88(3):29-36. [3] Robert TP, Marta GD, Alya D, et al. Global control and regional elimination of measles, 2000-2012[J]. Mmwr MMWR Morb Mortal Wkly Rep, 2014, 63(5):103-107. [4] 马超,郝利新,苏琪茹,等. 中国2014年麻疹流行病学特征分析[J]. 疾病监测,2015,30(10):818-823. [5] 苏琪茹,郝利新,马超,等. 中国2015—2016年麻疹流行病学特征分析[J]. 中国疫苗和免疫,2018,24(2):146-151. [6] 罗美玲,胡世雄,刘富强,等. 湖南省某福利院麻疹暴发疫情调查及传播链分析[J]. 实用预防医学,2017,24(5):576-579. [7] 黄晓玉,牙晓艳,危国强,等.中国消除麻疹进展研究[J]. 疾病监测与控制,2015, 9(5):309-315. [8] Hao L, Ma C, Wannemuehler KA, et al. Risk factors for measles in children aged 8 months–14 years in China after nationwide measles campaign: a multi-site case-control study, 2012—2013[J]. Vaccine,2016,34(51):6545-6552. [9] 卞琛,张建陶,凌良健,等. 常州市8月龄~14岁儿童麻疹传播影响因素分析[J]. 实用预防医学,2015,22(8):921-923. [10] 卞琛. 常州市麻疹流行趋势及传播影响因素的病例对照研究[D]. 苏州:苏州大学, 2013. [11] 丛艳丽, 孙丽, 李静, 等.河北省2010年强化免疫人群2015—2016年麻疹疫情分析[J]. 实用预防医学, 2019,26(9):1084-1086. [12] Clifford HD, Richmond P, Khoo SK, et al. SLAM and DC-SIGN measles receptor polymorphisms and their impact on antibody and cytokine responses to measles vaccine[J]. Vaccine, 2011, 29(33):5413. [13] Hungerford D, Cleary P, Ghebrehewet S, et al. Risk factors for transmission of measles during an outbreak: matched case-control study[J]. J Hosp Infect, 2014, 86(2):138-143. [14] 王海,刘翠娟,龚丽芬,等.河源市2004—2017年麻疹流行特征及消除进展[J].中国热带医学,2018,18(10):1040-1042. [15] 孟凡亚,陆志坚,沈永刚,等. 安徽省2015—2016年麻疹发病影响因素病例对照研究[J]. 中华疾病控制杂志,2017,21(6):581-585. [16] 陈保林,王希江,刘年强. 乌鲁木齐市流动儿童麻疹发病高危因素调查[J].疾病预防控制通报,2017(5):21-23,48. [17] 于雪静,张宏,史霞,等. 对孕妇进行麻疹认知干预以降低婴儿麻疹发病的效果研究[J]. 中国儿童保健杂志,2007,15(4):439-440.
2020, Vol. 27 
