Abstract：Objective To explore the impact of temperature on the morbidity of childhood hand, foot and mouth disease (HFMD) in Guangzhou city, and to provide a basis for formulating scientific and effective prevention and control measures. Methods We collected the data regarding the morbidity of HFMD in children aged 0-14 years and meteorological data in Guangzhou city during 2013-2017. The distributed lag non-linear model was used to analyze the effect of temperature on the morbidity of childhood HFMD. Results After controlling the confounders including relative humidity, wind speed and rainfall, the effect of temperature on HFMD was non-linear, and with a significant delayed effect. The effect of medium and high temperature on the incidence of HFMD appeared earlier and lasted longer. The cumulative incidence risk was the lowest when the temperature was 13.2℃ (RR=0.66, 95%CI: 0.64-0.98), but the highest when the temperature was 26.2℃ (RR=5.38, 95%CI: 5.16-5.62). No significant gender differences were found in the effect of temperature on HFMD, but the incidence of HFMD in children aged 0-1 and 7-14 years was more sensitive to temperature. Conclusions Temperature has a certain impact on the incidence of childhood HFMD in Guangzhou city. The incidence risk is found to be the highest when the temperature is 26.2℃, and children aged 0-1 and 7-14 years are sensitive populatio
刘伟, 董智强, 胡文穗, 康燕, 韩志刚, 侯建荣. 气温对广州市儿童手足口病发病影响的研究[J]. 实用预防医学, 2019, 26(8): 958-961.
LIU Wei, DONG Zhi-qiang, HU Wen-sui, KANG Yan, HAN Zhi-gang, HOU Jian-rong. Effect of temperature on the morbidity of childhood hand, foot and mouth disease in Guangzhou city. , 2019, 26(8): 958-961.
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