Abstract:Objective To explore the damage of low-dose radiation on the health of uranium miners. Methods All the employees of a uranium mine were divided into the exposure group and the control group (each n=81) based on works with or without harmful radiation factor exposure as well as age and gender composition. The hemogram, liver and kidney functions, lipidology, thyroid function, micronucleus detection rate and other indicators of the two groups were detected, and the differences were analyzed. Results No statistically significant differences were found in the abnormal rates of white blood cell(WBC), red blood cell(RBC), hemoglobin(Hb), platelet(PLT), percentage of neutrophils, percentage of lymphocytes, alanine aminotransferase(ALT), aspartate aminotransferase(AST), total protein(TP), uric acid(UA), cholesterol(CH), triglyceride(TG), high-density lipoprotein cholesterol(HDL-C)and low-density lipoprotein cholesterol(LDL-C)between the exposed group and the control group (P>0.05). There were statistically significant differences in total bilirubin (TBIL) and indirect bilirubin (IBIL)(38.27% vs. 22.22%, 38.27% vs. 22.22%, χ2=4.945, P=0.040)as well as in serum freetriiodothyronine (FT3)(51.85% vs. 34.57%, χ2=4.930, P=0.039)between the two groups, but no statistically significant differences were observed in serum free thyroxine (FT4) and serum thyroid stimulating hormone (TSH) (P>0.05). The micronucleus detection rate of the exposed group was 96.29%. Conclusions Low-dose radiation can cause liver and thyroid dysfunction and DNA damage in uranium miners.
陈香兰, 奉水东, 刘良丽, 高敏, 龙鼎新, 胡南. 低剂量辐射对铀矿工健康潜在的影响[J]. 实用预防医学, 2019, 26(6): 653-655.
CHEN Xiang-lan, FENG Shui-dong, LIU Liang-li, GAO Min, LONG Ding-xin, HU Nan. Potential impact of low-dose radiation on the health of uranium miners. , 2019, 26(6): 653-655.