Abstract:Objective To investigate the pathogenic characteristics of infectious diarrhea cases in Longshan County during 2015-2016, and to provide a scientific basis for formulating corresponding prevention and control measures. Methods We collected the information about diarrhoea cases meeting the inclusion criteria in the sentinel hospitals in Longshan County from May 2015 to April 2017. The fecal specimens were collected for detection of intestinal pathogenic bacteria and viruses, and then the data were analyzed. Results A total of 264 infectious diarrhea cases were investigated and detected. 98 cases were positive, with the total infection rate of 37.1%. The annual infection rates in 2015 and 2016 were 45% and 30.6% respectively, showing a statistically significant difference (χ2=5.851, P=0.016). The infection rates of bacteria and viruses were 13.3% and 25.4% respectively, with a statistically significant difference (χ2=12.443, P<0.001). A total of 13.3% (35/264) strains of pathogenic bacteria were isolated, and most of them were Salmonella (74.3%). A total of 29.5% (78/264) strains of viruses were isolated, and most of them (61.5%) were norovirus. The pathogenic spectrums of bacteria and viruses showed statistically significant differences (χ2=36.260, P<0.001; χ2=11.957, P=0.008). No statistically significant difference was found in the positive rate of pathogen detection and the pathogenic spectrums between genders (P>0.05). The positive detection rates of viruses in the youth group, the prime-aged group and the elderly group were 45.2%, 19.2% and 10.8% respectively, with statistically significant differences(χ2=24.175, P<0.001). No statistically significant differences were observed in the positive rate of bacterial detection and the pathogenic spectrums of bacteria and viruses among different age groups (all P>0.05). The positive rate of bacteria detected in July-September was high, and 22 Salmonella-positive samples were detected, accounting for 84.6% of the total. The positive rate of virus detection was found to be higher in November to March next year. A total of 36 norovirus-positive samples were detected in springand autumn, accounting for 75% of the total. Rotavirus infection presented peak characteristics in autumn and winter, and a total of 9 rotavirus-positive samples were detected, accounting for 60% of the total. Conclusions The main pathogens of the diarrhea cases occurred in Longshan County during 2015-2016 were Salmonella, norovirus and group A rotavirus, and the distribution of the cases showed obvious seasonal epidemic characteristics.