Abstract：Objective To investigate the rubella antibody levels of freshmen in Harbin City in 2015, and to provide a basis for developing rubella prevention and control strategies. Methods Multi-stage random sampling method was used to select 9 universities from Nangang District, Xiangfang District and Hulan District (each n=3) in Harbin City to serve as the monitored sites. ELISA was used for detection of rubella-specific immunoglobulin (IgG) antibody in serum among 1,089 freshmen in the 9 universities, and the rubella antibody levels of freshmen with different ages, gender, place of birth and history of immunization against rubella (HIAR) were compared.Results The antibody positive rate of rubella in the 1,089 freshmen was 83.01%. No statistically significant difference was found in the antibody positive rate of rubella between males and females (82.60% vs. 83.39%, χ2=0.12, P>0.05) as well as between freshmen with HIAR and ones without HIAR (85.27% vs. 76.47%, χ2=10.94,P=0.001). The antibody positive rate of rubella was found to be the lowest (45%) in the group aged 23-25 years (χ2=29.37, P<0.001). The antibody positive rate of rubella was lower in the freshmen from Heilongjiang Province than ones from other provinces (χ2=5.10, P=0.024). There were no statistically significant differences in the antibody positive rate of rubella among freshmen with different ethnic groups, universities and history of suffering from rubella (all P>0.05). Conclusions The overall antibody positive rate of rubella in the freshmen in Harbin City in 2015 was relatively high, but the elders were still at risk of developing rubella. It is necessary to conduct rubella supplementary immunization activities in the elder population, especially in the women of childbearing age.
2018, Vol. 25 
