Abstract:Objective To investigate the prevalence of chronic diseases and related risk factors in Wujin District of Changzhou City, and to provide evidence for formulating chronic disease-related prevention and control policies, health education and intervention measures. Methods Multi-stage stratified sampling method was used to respectively select 5,922, 9,094 and 7,904 permanent residents aged 18 years and above in Wujin District in 2010, 2012 and 2015, and a total of 22,920 participants were cumulatively surveyed. Their demographic information, life style and awareness of chronic disease-related knowledge were investigated by questionnaires. Physical examinations were performed to measure their height, weight, waist circumference and blood pressure. Laboratory testings were conducted to determine the levels of fasting blood glucose, total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). The data of the three surveys were analyzed and compared. Results The standardized prevalence rates of hypertension in 2010, 2012 and 2015 were 27.1%, 28.2% and 30.7% respectively, showing a gradually increasing tendency (χ2tendency=22.60,P<0.001). The standardized prevalence rates of diabetes were 6.1%, 6.5% and 7.8% respectively, displaying a gradually increasing tendency (χ2tendency=16.63, P<0.001). The standardized prevalence rates of dyslipidemia were 34.1%, 37.4% and 40.2% respectively, exhibiting a gradually increasing tendency (χ2tendency=53.70, P<0.001). The smoking rates in 2010, 2012 and 2015 were 25.6%, 21.5%, and 23.4% respectively. The smoking rates in males were 56.6%, 53.8% and 51.7% respectively, presenting a gradual decreasing tendency (χ2tendency=14.77, P=0.001). No statistically significant differences were found in the alcohol consumption rates in 2010, 2012 and 2015 between males and females (P>0.05). The prevalence rates of overweight were 33.9%, 35.5% and 33.8% respectively. The prevalence rates of obesity were 10.4%, 12.0% and 9.4% respectively. The prevalence rates of central obesity were 31.8%, 32.9% and 29.9% respectively. Statistically significant differences were observed in the prevalence rates of overweight and obesity among the three years (P<0.05). The awareness rates of chronic disease- related knowledge presented a gradually increasing tendency (all P<0.01). Conclusions The awareness rates of chronic disease prevention and control among permanent residents aged 18 years and above in Wujin District of Changzhou City in 2010-2015 were gradually increased, but the prevalence of chronic diseases was still at a high level and the risk factors were rife. It is necessary to take measures to comprehensively prevent and control the development of chronic diseases.